The instruction for medical use
of Contractubex Torgovoye medicine a name
of Contractubex
the International unlicensed name
Is not present
the Dosage form
Gel for external use, 20 g
Structure
of 100 g of drug contain
active agents: onions extract of liquid 10.00 g, heparin sodium (125 PIECES/mg) of 0.04 g, allantoin of 1.00 g,
excipients: sorbic acid, methylparahydroxybenzoate, gum ksantantanovy, polyethyleneglycol 200, oil perfumery 231616, the water purified.
The description
Gel from light-beige till light brown color, opaque, with a characteristic smell
Pharmacotherapeutic group
Drugs for treatment of wounds and ulcers. Drugs for hyper scarring treatment.
Other drugs for hyper scarring treatment
the ATX D03AX Code
the Pharmacological
Pharmacokinetics Heparin properties during 4 h in enough gets into connective tissue of a derma. Deep penetration is provided with a heparin combination with extract of Seraye onions and allantoin a transepidermal geparinization). When using drug Contractubex the system absorption is not observed.
A pharmacodynamics
the Combined drug which effect is caused by properties of the components which are its part. Renders fibrinolytic, anti-inflammatory (at the expense of onions extract), antitrombichesky (at the expense of heparin) and keratolichesky (at the expense of allantoin) action. Stimulates cellular regeneration without hyperplasia. Inhibits proliferation of keloid fibroblasts.
Indications
- hypertrophic and the keloid cicatrixes arising after surgeries, amputations, burns and injuries
- ankiloza of a contracture of joints, a palmar fibromatosis, traumatic tendinous contractures
- cicatricial strictures (atrophic hems)
Apply the Route of administration and doses to skin or a cicatricial surface several times in day and slightly rub before full absorption of gel.
At old dense hems for the night apply an occlusive bandage with gel. Treatment is carried out within several weeks or months.
At treatment of fresh hems it is necessary to avoid ultra-violet radiation, impact of cold and intensive massage.
Use in pediatrics
For children is aged more senior than 1 year gel it is possible to apply 1 or 2 times a day on a cicatricial surface. There are no sufficient data on use of the drug Contractubex for children till 1 year. Contractubex it is possible to use at children only according to the recommendation of the doctor.
Side effects
Often (≥1/100, & lt, 1/10)
- an itching, reddening, a teleangiectasia, a cicatricial atrophy
Sometimes (≥1/1000, & lt, 1/100)
- a skin hyperpegmentation, a skin atrophy
Frequency is unknown
- a swelling, pain in the site of application
- urticaria, rash, an itching, reddening, irritation of skin, a papule, a skin burn, burning sensation on skin, the feeling of squeezing of skin
- hypersensitivity (allergic reaction)
- pustulous rash
in general of Contractubex is very well transferred, even at long use. The itching which sometimes arises in the course of treatment by Contractubex, demonstrates fabric reorganization of hems, and usually does not demand the treatment termination.
Contraindications
- hypersensitivity to drug components
Medicinal interactions
Due to the lack of system absorption of drug, its use in combination with other drugs is possible.
Special indications
of Contractubex contains methylparahydroxybenzoate which can cause allergic reactions (perhaps late) and also sorbic acid which can cause local skin reactions (for example, contact dermatitis).
Pregnancy and the period of a lactation
the Risk at pregnancy and during breastfeeding is not established.
As safety was not studied, use is not recommended.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms: does not influence.
The overdose
is not revealed
the Form of release and packing
On 20 g of drug in tubas aluminum with a membrane and the screw-on plastic cap.On 1 tuba together with the instruction for medical use in the state and Russian languages place in a pack from cardboard.
To Store storage conditions in the dry place, at a temperature not above 25 °C.
To store out of children's reach!
A period of storage
3 years
the use Period after opening of 6 months.
Not to apply after an expiration date.
Prescription status
Without prescription
of ProizvoditelMerts Pharm GmbH and To.KGaAD-60318, Frankfurt am Main, Germany Ph. +49-69-1503-0, fax: +49-69-1503-200, e-mail: info@merz.de the Owner registration udostovereniyamerts Pharm GmbH, Germany
the Address of the organization admitting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods) Representative office to RK Pharm Garant GmbH in PK050002, Almaty, Zhibek-Zhola St. 64, office 305tel/fax: (727) 273 62 78, e-mail: pharmagarant.kaz@mail.ru
of Contractubex Torgovoye medicine a name
of Contractubex
the International unlicensed name
Is not present
the Dosage form
Gel for external use, 20 g
Structure
of 100 g of drug contain
active agents: onions extract of liquid 10.00 g, heparin sodium (125 PIECES/mg) of 0.04 g, allantoin of 1.00 g,
excipients: sorbic acid, methylparahydroxybenzoate, gum ksantantanovy, polyethyleneglycol 200, oil perfumery 231616, the water purified.
The description
Gel from light-beige till light brown color, opaque, with a characteristic smell
Pharmacotherapeutic group
Drugs for treatment of wounds and ulcers. Drugs for hyper scarring treatment.
Other drugs for hyper scarring treatment
the ATX D03AX Code
the Pharmacological
Pharmacokinetics Heparin properties during 4 h in enough gets into connective tissue of a derma. Deep penetration is provided with a heparin combination with extract of Seraye onions and allantoin a transepidermal geparinization). When using drug Contractubex the system absorption is not observed.
A pharmacodynamics
the Combined drug which effect is caused by properties of the components which are its part. Renders fibrinolytic, anti-inflammatory (at the expense of onions extract), antitrombichesky (at the expense of heparin) and keratolichesky (at the expense of allantoin) action. Stimulates cellular regeneration without hyperplasia. Inhibits proliferation of keloid fibroblasts.
Indications
- hypertrophic and the keloid cicatrixes arising after surgeries, amputations, burns and injuries
- ankiloza of a contracture of joints, a palmar fibromatosis, traumatic tendinous contractures
- cicatricial strictures (atrophic hems)
Apply the Route of administration and doses to skin or a cicatricial surface several times in day and slightly rub before full absorption of gel.
At old dense hems for the night apply an occlusive bandage with gel. Treatment is carried out within several weeks or months.
At treatment of fresh hems it is necessary to avoid ultra-violet radiation, impact of cold and intensive massage.
Use in pediatrics
For children is aged more senior than 1 year gel it is possible to apply 1 or 2 times a day on a cicatricial surface. There are no sufficient data on use of the drug Contractubex for children till 1 year. Contractubex it is possible to use at children only according to the recommendation of the doctor.
Side effects
Often (≥1/100, & lt, 1/10)
- an itching, reddening, a teleangiectasia, a cicatricial atrophy
Sometimes (≥1/1000, & lt, 1/100)
- a skin hyperpegmentation, a skin atrophy
Frequency is unknown
- a swelling, pain in the site of application
- urticaria, rash, an itching, reddening, irritation of skin, a papule, a skin burn, burning sensation on skin, the feeling of squeezing of skin
- hypersensitivity (allergic reaction)
- pustulous rash
in general of Contractubex is very well transferred, even at long use. The itching which sometimes arises in the course of treatment by Contractubex, demonstrates fabric reorganization of hems, and usually does not demand the treatment termination.
Contraindications
- hypersensitivity to drug components
Medicinal interactions
Due to the lack of system absorption of drug, its use in combination with other drugs is possible.
Special indications
of Contractubex contains methylparahydroxybenzoate which can cause allergic reactions (perhaps late) and also sorbic acid which can cause local skin reactions (for example, contact dermatitis).
Pregnancy and the period of a lactation
the Risk at pregnancy and during breastfeeding is not established.
As safety was not studied, use is not recommended.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms: does not influence.
The overdose
is not revealed
the Form of release and packing
On 20 g of drug in tubas aluminum with a membrane and the screw-on plastic cap.On 1 tuba together with the instruction for medical use in the state and Russian languages place in a pack from cardboard.
To Store storage conditions in the dry place, at a temperature not above 25 °C.
To store out of children's reach!
A period of storage
3 years
the use Period after opening of 6 months.
Not to apply after an expiration date.
Prescription status
Without prescription
of ProizvoditelMerts Pharm GmbH and To.KGaAD-60318, Frankfurt am Main, Germany Ph. +49-69-1503-0, fax: +49-69-1503-200, e-mail: info@merz.de the Owner registration udostovereniyamerts Pharm GmbH, Germany
the Address of the organization admitting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods) Representative office to RK Pharm Garant GmbH in PK050002, Almaty, Zhibek-Zhola St. 64, office 305tel/fax: (727) 273 62 78, e-mail: pharmagarant.kaz@mail.ru
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