What is Ketorolac?
Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) designed to relieve moderate to severe pain. It works by reducing inflammation and blocking the production of certain natural substances in your body that cause pain and swelling. This medication is often used for short-term pain management, such as after surgery, and is not intended for long-term use.
Why choose Ketorolac? It is known for its potent pain-relieving effects, comparable to opioid medications, but without the risk of dependence. Each tablet contains 10 mg of ketorolac tromethamine, and this packaging provides 20 tablets.
How is Ketorolac Used?
What are the indications for Ketorolac?
Ketorolac is used for the short-term management of moderate to severe acute pain. Common indications include:
- Postoperative pain relief.
- Acute musculoskeletal injuries.
- Pain conditions requiring rapid relief.
This medication is typically prescribed as a follow-up after intravenous or intramuscular ketorolac therapy in a hospital setting.
How should you take Ketorolac?
- Dosage for adults (16–64 years): One tablet (10 mg) taken orally every 4–6 hours, as needed. The maximum daily dose should not exceed 40 mg.
- Elderly or patients under 50 kg: Reduced frequency (every 6–8 hours) and lower doses may be recommended. Always follow medical advice.
- Duration: Treatment is limited to a maximum of 5 days to minimize the risk of adverse effects.
Important tips:
- Take the tablet with food or milk to reduce stomach upset.
- Avoid alcohol and other NSAIDs while on Ketorolac.
- Drink plenty of water to maintain hydration.
Who should avoid Ketorolac?
Ketorolac is contraindicated in the following cases:
- Allergies to NSAIDs or aspirin.
- Active gastrointestinal issues: ulcers, bleeding, or perforation.
- Severe renal impairment.
- Bleeding disorders or concurrent anticoagulant use.
- Pregnancy and breastfeeding.
- Patients under 16 years.
Patients with conditions such as asthma, cardiovascular disease, or dehydration should use Ketorolac with caution and under medical supervision.
What Are the Potential Side Effects?
Common side effects:
- Nausea, vomiting, or stomach pain.
- Drowsiness or dizziness.
- Headache.
Serious side effects (rare):
- Gastrointestinal bleeding or ulcers.
- Allergic reactions such as rash, swelling, or difficulty breathing.
- Kidney dysfunction, marked by decreased urine output or swelling.
- Cardiovascular issues like hypertension or heart failure.
If any severe side effects occur, stop using Ketorolac immediately and seek medical attention.
Special Warnings
Risk of bleeding:
Ketorolac can inhibit platelet aggregation, prolonging bleeding time. Avoid using it in conjunction with anticoagulants like warfarin or high-dose aspirin.
Kidney and liver monitoring:
Patients with existing kidney or liver issues should undergo regular testing while on Ketorolac.
Drug interactions:
Avoid combining Ketorolac with:
- Other NSAIDs or corticosteroids (increased risk of GI bleeding).
- Diuretics (potential for reduced kidney function).
- Lithium or methotrexate (risk of toxicity)
Storage Instructions
- Keep Ketorolac at room temperature (20–25°C or 68–77°F), away from direct sunlight and moisture.
- Store in its original packaging to protect from humidity.
- Keep out of reach of children.
