Exifine® (Terbinafine) 250 mg, 16 tablets

What is Exifine® (Terbinafine)?

Exifine® contains Terbinafine, an antifungal medication that works effectively against a variety of fungal infections.

With each tablet containing 250 mg of Terbinafine, this medication is designed to combat stubborn fungal infections affecting both skin and nails, bringing relief to those struggling with persistent symptoms.

What Does Exifine® Treat?

Exifine® is primarily used for the treatment of various fungal conditions, including:

• Onychomycosis (Nail Fungus): Terbinafine targets dermatophytes responsible for nail infections, helping restore healthy nail growth.
• Dermatophytosis and Scalp Infections: Effective against fungal conditions like Tinea corporis (body ringworm), Tinea cruris (jock itch), Tinea pedis (athlete’s foot), and Tinea capitis (scalp ringworm).
• Candidiasis and Extensive Fungal Skin Infections: Suitable for serious or widespread skin infections caused by yeast, particularly when localized treatments are insufficient.

How Does Exifine® Work?

Terbinafine, the active component of Exifine®, interferes with the fungal cell membrane, effectively killing the fungi and preventing its growth. It provides a systematic approach to fighting infections that may be resistant to topical solutions, making it ideal for difficult-to-treat fungal conditions.

Who Should Not Use Exifine®?

Before starting Exifine®, it's essential to consider the following:

• Liver Issues: People with liver conditions should avoid using Exifine®, as it can potentially worsen liver function.
• Pregnancy and Breastfeeding: The use of Exifine® is not recommended during pregnancy or breastfeeding due to limited data on safety.
• Children Under 6 Years Old: It is also unsuitable for young children, particularly those weighing under 40 kg.

What Should You Know Before Taking Exifine®?

• Liver Monitoring: Liver function tests are advised before starting treatment, and periodic monitoring is recommended during use to detect any signs of liver toxicity early.
• Potential Drug Interactions: Terbinafine can interact with certain medications. For instance, cimetidine may reduce its clearance, while rifampicin may increase it. If you are on other medications like antidepressants or beta-blockers, consult your doctor to adjust doses appropriately.

What Are the Common Side Effects of Exifine®?

Most individuals tolerate Exifine® well, but like any medication, side effects can occur. Commonly reported side effects include:

• Gastrointestinal Symptoms: These may include nausea, abdominal pain, or diarrhea.
• Skin Reactions: Rash or hives might appear in some cases.
• Headaches and Muscle Pain: Some users report headaches or joint and muscle pain during treatment.

If any severe symptoms occur, such as yellowing of the skin or persistent nausea, these may indicate liver issues and require immediate medical attention.

How to Use Exifine® Tablets?

Dosage and Duration

• Adults: The recommended dosage for adults is 250 mg once a day.
• Treatment Duration: The length of treatment depends on the infection type:
  • For skin infections like athlete’s foot, treatment can last from 2 to 6 weeks.
  • Nail infections might require a longer period, typically from 6 weeks to 3 months, depending on the nail growth rate and the severity of the infection.

Special Considerations for Usage

• Older Adults: There is no specific adjustment needed for older adults, though monitoring liver and kidney function is crucial.
• Children: Use in children is limited due to insufficient safety data, making Exifine® not generally recommended for pediatric use.

How Should You Take Exifine® Tablets?

Take the tablets orally with a glass of water, at the same time each day for consistency.

You can take Exifine® with or without food.

Consistency helps in ensuring the best results from the medication.

What If You Miss a Dose?

If you miss a dose, take it as soon as you remember.

If it’s nearly time for your next dose, skip the missed dose.

Do not double up to compensate for a missed one, as it may increase the risk of side effects.

What Are the Serious Side Effects to Watch For?

• Liver-Related Symptoms: Be alert to symptoms like persistent nausea, fatigue, dark urine, or yellowing of the skin and eyes. These signs could indicate liver issues.
• Severe Skin Reactions: Stop taking Exifine® if you develop severe rashes or blistering of the skin, as this could be a sign of a rare but serious condition.
• Blood Cell Changes: Though very rare, Exifine® can sometimes cause changes in blood cell counts, leading to symptoms like easy bruising or frequent infections.

How to Store Exifine® Tablets?

Store Exifine® in a dry place, away from direct sunlight, at temperatures below 25°C (77°F).

Keep it out of reach of children to ensure safety.

Can Exifine® Affect Daily Activities?

While Exifine® has not been specifically studied for its impact on activities like driving, it may cause dizziness in some people.

If you experience dizziness, avoid driving or operating heavy machinery.