The instruction for medical use
of Essliver medicine H
the Trade name
Essliver of N
the International unlicensed name
Is not present
the Dosage form
of the Capsule, 300 mg
Structure
One capsule contains
active agent: essential phospholipids of 300 mg,
excipients: sodium methylparahydroxybenzoate, sodium propilparagidroksibenzoat, dinatrium edetat, butyl hydroxytoluene, talc, aluminum magnesium silicate hydrate,
structure of the capsule: methylparahydroxybenzoate, propilparagidroksibenzoat, the titan dioxide, water purified, gelatin.
Description
Solid gelatin capsules of No. in size 0 white colors. Capsule contents - powder of light brown color. Existence of particles in the form of the condensed powdery weight is allowed.
Pharmacotherapeutic group
Drugs for treatment of diseases of a liver.
The code of automatic telephone exchange A05BA
the Pharmacological
Pharmacokinetics Near properties of 90% of phospholipids is soaked up in a small intestine, their most part is split by means of a phospholipase And to 1-acyl-lizofosfatidilkholina which 50% are acetylated again to polyunsaturated phosphatidylsincaline which gets to blood on absorbent vessels and from there, mainly in the connected state with lipoproteins of high density, gets into a liver. Elimination half-life (T1/2) of a choline component makes 66 h, and unsaturated fatty acids – 32 h. It is removed, generally with a stake.
Pharmacodynamics
Hepatoprotective means. The phospholipids which are a part of drug are basic elements in structure of a cellular cover and mitochondrions of hepatocytes. Regulates lipidic and carbohydrate metabolism, improves a functional condition of a liver and its disintoxication function, promotes preservation and recovery of structure of hepatocytes, slows down forming of connective tissue in a liver.
Indications
- acute and chronic hepatitis
- fat dystrophy of a liver of various genesis
- toxic hepatitis, alcoholic hepatitis, medicinal damages of a liver
the Route of administration
For intake. To adults and children 12 years are more senior: on 2 capsules 2-3 times a day at meal time, washing down with a large amount of liquid. Duration of a course of treatment is established by the doctor individually depending on disease severity.
Side effects
- allergic reactions (rash, urticaria, an itching),
- feeling of discomfort in epigastric area, easy ease of a chair, diarrhea. Administration of drug has to be stopped in case of above-mentioned side effects, especially, in case of hypersensitivity. The patient has to see a doctor who will estimate gravity of a symptom and will take adequate measures for its elimination.
Contraindications
- hypersensitivity to drug components
- children's age up to 12 years
Medicinal interactions
Are possible medicinal interactions with anticoagulants. In case of a concomitant use the patient needs to consult with the doctor for correction of a dose of anticoagulant.
Special
instructions Pregnancy and period of a lactation. Researches of safety and efficiency of drug at pregnancy and a lactation are absent. Drug is not recommended to be used at pregnancy and in the period of a lactation.
Use in pediatrics
of the Research of safety and efficiency of use of drug for children is younger than 12 years are absent.
Drug should not be used at children 12 years are younger.
The feature of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
does not influence.
Overdose
Cases of overdose are not revealed
the Form of release and packing
On 10 capsules place in blister strip packaging from a film of polyvinylchloride and aluminum foil.
On 3 planimetric packs together with the instruction for medical use in the state and Russian languages place in a pack from cardboard.
Storage conditions
In the dry, protected from light place at a temperature not over 25 of 0C.
To store out of children's reach!
3 years
not to apply a period of storage after an expiration date.
Prescription status
Without prescription
Nabros Pharm Pvt. Ltd. Producer, India
National highway 8 Kajizipura Kheda
the Name and a camp of the owner of the registration certificate
Nabros Pharm Pvt. Ltd., India
National highway 8 Kajizipura Kheda
the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products: Representation Nabros Pharm Pvt. Ltd. in the Republic of Kazakhstan, the Microdistrict of Mamyr 3, 3A, 050036, Almaty, the Republic of Kazakhstantel.: +7 (727) 226 13 14, e-mail: nabros.almaty@gmail.com
of Essliver medicine H
the Trade name
Essliver of N
the International unlicensed name
Is not present
the Dosage form
of the Capsule, 300 mg
Structure
One capsule contains
active agent: essential phospholipids of 300 mg,
excipients: sodium methylparahydroxybenzoate, sodium propilparagidroksibenzoat, dinatrium edetat, butyl hydroxytoluene, talc, aluminum magnesium silicate hydrate,
structure of the capsule: methylparahydroxybenzoate, propilparagidroksibenzoat, the titan dioxide, water purified, gelatin.
Description
Solid gelatin capsules of No. in size 0 white colors. Capsule contents - powder of light brown color. Existence of particles in the form of the condensed powdery weight is allowed.
Pharmacotherapeutic group
Drugs for treatment of diseases of a liver.
The code of automatic telephone exchange A05BA
the Pharmacological
Pharmacokinetics Near properties of 90% of phospholipids is soaked up in a small intestine, their most part is split by means of a phospholipase And to 1-acyl-lizofosfatidilkholina which 50% are acetylated again to polyunsaturated phosphatidylsincaline which gets to blood on absorbent vessels and from there, mainly in the connected state with lipoproteins of high density, gets into a liver. Elimination half-life (T1/2) of a choline component makes 66 h, and unsaturated fatty acids – 32 h. It is removed, generally with a stake.
Pharmacodynamics
Hepatoprotective means. The phospholipids which are a part of drug are basic elements in structure of a cellular cover and mitochondrions of hepatocytes. Regulates lipidic and carbohydrate metabolism, improves a functional condition of a liver and its disintoxication function, promotes preservation and recovery of structure of hepatocytes, slows down forming of connective tissue in a liver.
Indications
- acute and chronic hepatitis
- fat dystrophy of a liver of various genesis
- toxic hepatitis, alcoholic hepatitis, medicinal damages of a liver
the Route of administration
For intake. To adults and children 12 years are more senior: on 2 capsules 2-3 times a day at meal time, washing down with a large amount of liquid. Duration of a course of treatment is established by the doctor individually depending on disease severity.
Side effects
- allergic reactions (rash, urticaria, an itching),
- feeling of discomfort in epigastric area, easy ease of a chair, diarrhea. Administration of drug has to be stopped in case of above-mentioned side effects, especially, in case of hypersensitivity. The patient has to see a doctor who will estimate gravity of a symptom and will take adequate measures for its elimination.
Contraindications
- hypersensitivity to drug components
- children's age up to 12 years
Medicinal interactions
Are possible medicinal interactions with anticoagulants. In case of a concomitant use the patient needs to consult with the doctor for correction of a dose of anticoagulant.
Special
instructions Pregnancy and period of a lactation. Researches of safety and efficiency of drug at pregnancy and a lactation are absent. Drug is not recommended to be used at pregnancy and in the period of a lactation.
Use in pediatrics
of the Research of safety and efficiency of use of drug for children is younger than 12 years are absent.
Drug should not be used at children 12 years are younger.
The feature of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
does not influence.
Overdose
Cases of overdose are not revealed
the Form of release and packing
On 10 capsules place in blister strip packaging from a film of polyvinylchloride and aluminum foil.
On 3 planimetric packs together with the instruction for medical use in the state and Russian languages place in a pack from cardboard.
Storage conditions
In the dry, protected from light place at a temperature not over 25 of 0C.
To store out of children's reach!
3 years
not to apply a period of storage after an expiration date.
Prescription status
Without prescription
Nabros Pharm Pvt. Ltd. Producer, India
National highway 8 Kajizipura Kheda
the Name and a camp of the owner of the registration certificate
Nabros Pharm Pvt. Ltd., India
National highway 8 Kajizipura Kheda
the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products: Representation Nabros Pharm Pvt. Ltd. in the Republic of Kazakhstan, the Microdistrict of Mamyr 3, 3A, 050036, Almaty, the Republic of Kazakhstantel.: +7 (727) 226 13 14, e-mail: nabros.almaty@gmail.com
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