Derinat 0.25% 10 ml solution (external application) .
- $41.00
The instruction for medical use
of DERINAT® medicine
the Trade name
of Derinat®
the International unlicensed name
Is not present
the Dosage form
Solution for external and topical administration of 0.25%, 10 ml
Structure
of 100 ml of solution contain
active agent - sodium dezoksiribonukleat 0.25 g
(from milts of salmons),
excipients: sodium chloride, water for injections.
Description
Transparent colourless liquid.
Pharmacotherapeutic group
Antineoplastic drugs and immunomodulators. Other immunostimulators.
The code of automatic telephone exchange LO3AX
the Pharmacological
Dezoksiribonukleat Pharmacokinetics properties of sodium at topical administration is quickly soaked up and distributed in peripheral fabrics and most in bodies retikulo - an endothelial system with participation of an endolymphatic way of transport. In a phase of intensive intake of drug in blood there is a redistribution between plasma and uniform elements of blood. Dezoksiribonukleat of sodium is metabolized in an organism to nucleotides in peripheral fabrics further to uric acid, β – alanine and β– aminoisobutyrate in a liver. Metabolites are excreted from an organism with a stake (22%) and more with urine (78%).
The pharmacodynamics
of Derinat® activates cell-mediated and antibody-mediated immunity. Optimizes specific reactions against fungal, viral and bacterial infections. Drug stimulates reparative and regenerator processes, normalizes a condition of fabrics and bodies in dystrophies of vascular origin. Деринат® promotes healing of trophic ulcers of various etiology. Деринат® promotes fast healing of deep burns, considerably accelerating dynamics of epithelization. At restoration of ulcer formations on a mucous membrane under action of Derinata® there is a bezrubtsovy restoration. Drug does not possess teratogenic and cancerogenic actions.
Indications
of Monoterapiya
- prevention and treatment of the acute respiratory viral infections (ARVI)
- inflammatory and dystrophic diseases of eyes (conjunctivitis, blepharitis, a uveitis)
- inflammatory diseases of mucous membranes of an oral cavity (stomatitis, an ulitis, aphthous ulcers)
- chronic gynecologic diseases of fungal, bacterial and other etiology
as a part of complex therapy
- acute and chronic diseases of a nasal cavity and his bosoms (rhinitis, sunusit, antritis, a frontal sinusitis)
- hemorrhoids
- damages of skin (trophic ulcers, it is long not healing and contaminated wounds, including in diabetes, gangrene, burns, frostbites, post-beam necroses of skin and mucous)
the Route of administration and doses
appoint Drug to children from the first day of life and the adult.
For prevention of a SARS drug is dug in on 2 drops in each nasal course by 2-4 times a day within 1 month.
At emergence of symptoms of a SARS, drug is dug in on 2-3 drops in each nasal course every 1.0-1.5 hour, within the first day, further - on 2-3 drops in each nasal course 3-4 times a day. Duration of a course of treatment – before disappearance of symptoms of a disease.
In inflammatory diseases of a nasal cavity and adnexal bosoms drug is dug in on 3-5 drops in each nasal course of 4-6 times a day.
Duration of a course of treatment is 7-15 days.
In inflammatory diseases of an oral cavity make rinsing by drug of 4-6 times a day (1 bottle on 1-2 rinsing). Duration of a course of treatment is 5-10 days.
In chronic gynecologic diseases of fungal, bacterial and other etiology: intra vaginal irrigation of a neck of the uterus or intra vaginal introduction of tampons with drug on 5 ml of 0.25% of solution for the procedure, 1-2 times a day. Duration of a course of treatment is 10-14 days.
In hemorrhoids drug of initial concentration is appointed in the form of microclysters in a rectum on 15-40 ml. Duration of a course of treatment is 4-10 days.
In a serious inflammatory and dystrophic illness of eyes drug is dug in in eyes on 1-2 drops by 2-3 times a day. Duration of a course of treatment is 14-45 days.
In post-beam necroses of skin and mucous membranes, at it is long not healing wounds, burns, frostbites, trophic ulcers of various etiology, gangrenes 3-4 times during the day apply application bandages to the struck places (a gauze in two layers) with the drug applied on it or carry out processing of the struck surface by drug from the spray of 4-5 times a day on 10-40 ml. Duration of a course of treatment is 1-3 months.
Side effects
- allergic reactions: burning,
naggers Protivopokazaniya
- hypersensitivity to drug components
Medicinal interactions
At topical administration it is not compatible to ointments on a fat basis and hydrogen peroxide.
Special instructions
At sphacelisms under the influence of drug the spontaneous sloughing with restoration of an integument is noted. In open wounds and burns the analgeziruyushchy action is observed.
Use in pediatrics
Is applied at children from the first days of life.
Pregnancy and the period of a lactation
Drug can be used during pregnancy and during feeding by a breast.
The feature of influence of medicine on ability to run the vehicle or other potentially dangerous mechanisms
does not influence.
Overdose
Cases of overdose are not established.
A form of release and packing
On 10 ml in the glass bottles droppers corked by a cover SANO dropper. The bottle dropper, with the pasted label, is placed together with the instruction for medical use in the state and Russian languages in a pack from cardboard.
To Store storage conditions in the place protected from light, at a temperature from 4 °C to 20 °C.
To store out of children's reach.
Not to use a period of storage of 5 years after an expiration date.
Prescription status
Without prescription
CJSC FP Technomedservice Producer, Russia, 105318, Moscow, Mironovskaya St., 33, building 28, ph. (495) 739-52-98, fax (495) 234-46-99.
The address of the organization of the accepting claim from the consumer on quality of drug in the territory of the Republic of Kazakhstan: SP Nesterenko N. A., Republic of Kazakhstan, 050000, Almaty, Furmanov St., 128, office 16, ph./fax (727) 2796659, e-mail: ip_n_nesterenko@list.ru.
of DERINAT® medicine
the Trade name
of Derinat®
the International unlicensed name
Is not present
the Dosage form
Solution for external and topical administration of 0.25%, 10 ml
Structure
of 100 ml of solution contain
active agent - sodium dezoksiribonukleat 0.25 g
(from milts of salmons),
excipients: sodium chloride, water for injections.
Description
Transparent colourless liquid.
Pharmacotherapeutic group
Antineoplastic drugs and immunomodulators. Other immunostimulators.
The code of automatic telephone exchange LO3AX
the Pharmacological
Dezoksiribonukleat Pharmacokinetics properties of sodium at topical administration is quickly soaked up and distributed in peripheral fabrics and most in bodies retikulo - an endothelial system with participation of an endolymphatic way of transport. In a phase of intensive intake of drug in blood there is a redistribution between plasma and uniform elements of blood. Dezoksiribonukleat of sodium is metabolized in an organism to nucleotides in peripheral fabrics further to uric acid, β – alanine and β– aminoisobutyrate in a liver. Metabolites are excreted from an organism with a stake (22%) and more with urine (78%).
The pharmacodynamics
of Derinat® activates cell-mediated and antibody-mediated immunity. Optimizes specific reactions against fungal, viral and bacterial infections. Drug stimulates reparative and regenerator processes, normalizes a condition of fabrics and bodies in dystrophies of vascular origin. Деринат® promotes healing of trophic ulcers of various etiology. Деринат® promotes fast healing of deep burns, considerably accelerating dynamics of epithelization. At restoration of ulcer formations on a mucous membrane under action of Derinata® there is a bezrubtsovy restoration. Drug does not possess teratogenic and cancerogenic actions.
Indications
of Monoterapiya
- prevention and treatment of the acute respiratory viral infections (ARVI)
- inflammatory and dystrophic diseases of eyes (conjunctivitis, blepharitis, a uveitis)
- inflammatory diseases of mucous membranes of an oral cavity (stomatitis, an ulitis, aphthous ulcers)
- chronic gynecologic diseases of fungal, bacterial and other etiology
as a part of complex therapy
- acute and chronic diseases of a nasal cavity and his bosoms (rhinitis, sunusit, antritis, a frontal sinusitis)
- hemorrhoids
- damages of skin (trophic ulcers, it is long not healing and contaminated wounds, including in diabetes, gangrene, burns, frostbites, post-beam necroses of skin and mucous)
the Route of administration and doses
appoint Drug to children from the first day of life and the adult.
For prevention of a SARS drug is dug in on 2 drops in each nasal course by 2-4 times a day within 1 month.
At emergence of symptoms of a SARS, drug is dug in on 2-3 drops in each nasal course every 1.0-1.5 hour, within the first day, further - on 2-3 drops in each nasal course 3-4 times a day. Duration of a course of treatment – before disappearance of symptoms of a disease.
In inflammatory diseases of a nasal cavity and adnexal bosoms drug is dug in on 3-5 drops in each nasal course of 4-6 times a day.
Duration of a course of treatment is 7-15 days.
In inflammatory diseases of an oral cavity make rinsing by drug of 4-6 times a day (1 bottle on 1-2 rinsing). Duration of a course of treatment is 5-10 days.
In chronic gynecologic diseases of fungal, bacterial and other etiology: intra vaginal irrigation of a neck of the uterus or intra vaginal introduction of tampons with drug on 5 ml of 0.25% of solution for the procedure, 1-2 times a day. Duration of a course of treatment is 10-14 days.
In hemorrhoids drug of initial concentration is appointed in the form of microclysters in a rectum on 15-40 ml. Duration of a course of treatment is 4-10 days.
In a serious inflammatory and dystrophic illness of eyes drug is dug in in eyes on 1-2 drops by 2-3 times a day. Duration of a course of treatment is 14-45 days.
In post-beam necroses of skin and mucous membranes, at it is long not healing wounds, burns, frostbites, trophic ulcers of various etiology, gangrenes 3-4 times during the day apply application bandages to the struck places (a gauze in two layers) with the drug applied on it or carry out processing of the struck surface by drug from the spray of 4-5 times a day on 10-40 ml. Duration of a course of treatment is 1-3 months.
Side effects
- allergic reactions: burning,
naggers Protivopokazaniya
- hypersensitivity to drug components
Medicinal interactions
At topical administration it is not compatible to ointments on a fat basis and hydrogen peroxide.
Special instructions
At sphacelisms under the influence of drug the spontaneous sloughing with restoration of an integument is noted. In open wounds and burns the analgeziruyushchy action is observed.
Use in pediatrics
Is applied at children from the first days of life.
Pregnancy and the period of a lactation
Drug can be used during pregnancy and during feeding by a breast.
The feature of influence of medicine on ability to run the vehicle or other potentially dangerous mechanisms
does not influence.
Overdose
Cases of overdose are not established.
A form of release and packing
On 10 ml in the glass bottles droppers corked by a cover SANO dropper. The bottle dropper, with the pasted label, is placed together with the instruction for medical use in the state and Russian languages in a pack from cardboard.
To Store storage conditions in the place protected from light, at a temperature from 4 °C to 20 °C.
To store out of children's reach.
Not to use a period of storage of 5 years after an expiration date.
Prescription status
Without prescription
CJSC FP Technomedservice Producer, Russia, 105318, Moscow, Mironovskaya St., 33, building 28, ph. (495) 739-52-98, fax (495) 234-46-99.
The address of the organization of the accepting claim from the consumer on quality of drug in the territory of the Republic of Kazakhstan: SP Nesterenko N. A., Republic of Kazakhstan, 050000, Almaty, Furmanov St., 128, office 16, ph./fax (727) 2796659, e-mail: ip_n_nesterenko@list.ru.
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