Anuzol 10s rectal suppositories

The instruction for medical use of Anuzol Torgovoye medicine the name Anuzol Mezhdunarodnoye the unlicensed name Is not present the Dosage form. Suppositories rectal Structure 1 suppository contains active agents: a xeroform of 0.10 g, a belladonna of extract dense in terms of the maintenance of the sum of alkaloids of 1.5% 0.02 g, zinc of sulfate of 0.05 g, excipients: solid fat, glycerin. The description Suppositories of yellow color with a brownish or greenish shade, with a xeroform smell. On a cut the existence of an air core or funneled deepening is allowed. Emergence of a white plaque on a suppository surface is allowed. Pharmacotherapeutic group Cardiovascular system. Vazoprotektora. Means for treatment of hemorrhoids and anal cracks for topical administration. Other means for treatment of hemorrhoids and anal cracks for topical administration. Other drugs and their combinations. The ATX C05AX03 code the Pharmacological Pharmacokinetics At properties introduction of a suppository to a rectum effect of drug is shown in 15-90 minutes. Duration of resorptive effect of alkaloids fluctuates from 2 to 6 hours. A pharmacodynamics the Antihemorrhoidal combined means. Anuzol possesses spasmolytic, anti-inflammatory, antiseptic, soothing, the local anti-inflammatory, knitting and drying action. A xeroform (tribromfenolit bismuth) – the antiseptic, anti-inflammatory, knitting and drying means. Belladonna extract (belladonna extract) – renders M-holinoblokiruyushchee and spasmolytic action, reduces a tone of muscles of digestive tract. Zinc sulfate - astringent, an antiseptic agent. Indications Hemorrhoids, anal fissures at adults. To Apply a route of administration and doses rektalno. To enter into a rectum – on 1 suppository 3 times a day and after each defecation. The maximum daily dose – 7 suppositories. Duration of use depends on disease severity and expressiveness of medical effect. Side effects - dryness in a mouth, feeling of thirst, disturbance of flavoring feelings, a dysphagy, reduction of motility of intestines up to an atony, reduction of a tone of biliary tract and a gall bladder, a constipation, diarrhea - difficulty and a delay of urination - tachycardia, heart consciousness, arrhythmia, including premature ventricular contraction, myocardium ischemia - face reddening, feeling of inflows - a headache, dizziness, nervousness, insomnia - expansion of pupils, photophobia, accommodation paralysis, increase in intraocular pressure, temporary visual disturbances - cough with a viscous phlegm - skin rash, a small tortoiseshell, exfoliative dermatitis - anaphylactic reactions, an acute anaphylaxis - sweating reduction, xeroderma, a dysarthtia, burning in an anus. In case of any undesirable phenomena it is necessary to see a doctor. Contraindications - hypersensitivity to drug components - an atrial fibrillation, tachycardia, chronic heart failure, coronary heart disease, a mitral stenosis, heavy arterial hypertension - acute bleeding - a thyrotoxicosis - a hyper thermal syndrome - the digestive tract diseases which are followed by impassability (gullet achalasia, a pyloric stenosis, an intestines atony) - closed-angle glaucoma - a liver and renal failure - gravis myasthenia - prostate adenoma in a decompensation stage, a sharp ischuria - pregnancy and the period of a lactation - children's age up to 18 years Medicinal interactions At use of drug with inhibitors of a monoaminooxidase arise heart arrhythmia, with quinidine, novokainamidy – synergism of cholinolytic effect, with drugs of a lily of the valley is observed, with tannin the physical and chemical interaction is observed that leads to mutual easing of effects. Anuzol reduces duration and depth of effect of drugs, weakens analgetic effect of opiates. At simultaneous use with Dimedrol or isopromethazine the effect of atropine amplifies, nitrates, a haloperidol, corticosteroids for system use – the probability of increase in intraocular pressure increases, with sertraline – the depressive effect of both drugs, with Spironolactonum amplifies, minoksidily – the effect of Spironolactonum and a minoksidil decreases, with penicillin – the effect of both drugs amplifies, with nizatidiny – action of a nizatidin amplifies, with ketokonazoly – absorption of a ketokonazol decreases, with ascorbic acid and attapulgite – Anuzol's action decreases, with pilocarpine – the effect of pilocarpine at treatment of glaucoma decreases, with oksprenolony – the antihypertensive effect of drug decreases. Under the influence of Octadinum the reduction of hyposecretory effect of drug is possible, weakens action of M-cholinomimetics and antikholinesterazny means. At simultaneous use with sulfanamide drugs the risk of damage of kidneys, with the drugs containing potassium – possibly formation of ulcers of intestines increases, with nonsteroid prtivovospalitelny means – the risk of formation of stomach ulcers and bleedings increases. Anuzol's action can amplify at simultaneous use of other drugs with antimuskarinovy effect: M-holinoblokatorov, protivoparkinsonichesky drugs (amantadin), spasmolysants, some antihistamines, drugs of group of phenyl propyl ketone, fenotiazin, dispiramid, quinidine and tricyclic antidepressants, non-selective inhibitors of the return neuronalny capture of monoamines. Oppression of a vermicular movement under the influence of Anuzol can lead to change of absorption of other medicines. Special instructions With care to apply to patients with a prostatauxe without obstruction of urinary tract, with a Down syndrome, in cerebral palsy, a reflux esophagitis, hernias of an esophageal opening of the diaphragm which is combined about a reflux esophagitis, nonspecific ulcer colitis, megacolon, to patients with xerostomia, patients of advanced age or the weakened patients, in chronic diseases of lungs without reversible obstruction, in chronic diseases of lungs, proceeding with low producing a dense phlegm which difficult separates, especially at the weakened patients, in vegetative (autonomous) neuropathy. Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms Considering a possibility of emergence of such side reactions as dizziness, hallucinations, accommodation disturbance, during use of drug it is necessary to refrain from control of motor transport or work with other mechanisms. Overdose Symptoms: strengthening of manifestations of side reactions, nausea, vomiting, lowering of arterial pressure, excitement, tremor, spasms, insomnia, drowsiness, hallucinations, irritability, hyperthermia. Oppression of the central nervous system, suppression of activity of the respiratory and vasomotor centers, urination delay, hyperthermia. Treatment. Gastric lavage, paranteralno introductions of cholinomimetics and antikholinesterazny means. At a hyperthermia damp rubdowns and febrifuges are shown, at excitement – administration of thiopental of sodium or hydroxybutyrate of sodium at a mydriasis – locally in the form of eye drops Phosphacolum, physostigmine, pilocarpine. In case of development of an attack of glaucoma immediately in a conjunctival sac to dig in 1% pilocarpine solution each hour on 2 drops and to subcutaneously enter 1 ml of 0.05% of solution of a prozerin 3-4 times a day. The form of release and packing On 5 suppositories place in planimetric bezjyacheykovy packing from a film polyvinylchloride. On 2 planimetric packs together with the instruction for medical use in the state and Russian languages put in a pack from cardboard for a retail container. Storage conditions In original packing at a temperature not above 15 °C. To store out of children's reach. Period of storage 2 years. Not to apply after an expiration date. Prescription status Without prescription Ukraine PJSC Monpharm Producer, 19100, Cherkassk Region, Monastyrishche, Zavodskaya St., 8. The owner of the registration certificate of PJSC Monpharm, Ukraine the Name, the address and a contact information (phone, the fax, e-mail) of the organization in the territory of the Republic of Kazakhstan, the accepting claim (offer) on quality of medicines from consumers and responsible for post-registration observation of safety of medicine: ALDIMED LLP, Republic of Kazakhstan, Almaty, 050051, mdt. Samal-1, house 1.
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