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Afobazole (Fabomotizole) 10 mg, 60 tablets

  • $24.00
Sku: 50ac0292a1c2
Ingredient: Fabomotizole
Cas No.: 173352-21-1
ATC Code: N05BX04

What is Afobazole?

Afobazole (Fabomotizole) is a non-benzodiazepine anxiolytic medication designed to relieve anxiety and stress without causing sedation or dependency. It is known for its ability to promote natural recovery of nerve cells, making it an effective treatment for anxiety-related conditions.


Afobazole is particularly suitable for individuals with asthenic personality traits such as heightened vulnerability, emotional instability, and excessive worry.


Afobazole was developed by the Zakusov Research Institute of Pharmacology under the Russian Academy of Medical Sciences, led by academician S.B. Seredenin, after years of research to create a selective anxiolytic that combines the efficacy of traditional benzodiazepine tranquilizers without their associated side effects. This innovative medication was formulated as a safer alternative for anxiety management.


How Does Afobazole Work?

Afobazole works by interacting with sigma-1 receptors in the brain, which helps stabilize GABA (gamma-aminobutyric acid) and benzodiazepine receptors.

This action restores the receptors' sensitivity to the body's natural calming mechanisms.

Unlike traditional anxiety medications, Afobazole does not depress the central nervous system, which means it doesn’t cause drowsiness, muscle relaxation, or dependence.


What Are the Benefits of Afobazole?

Afobazole offers several advantages, including:

  • No daytime drowsiness: It helps reduce anxiety without causing sedation.
  • No impairment of memory and concentration: Users can maintain cognitive functions while using this medication.
  • No muscle relaxation: Unlike many anxiolytics, Afobazole does not cause muscle weakness.
  • No addiction risk: The medication does not lead to dependency or withdrawal symptoms after discontinuation.


When Can You Expect to See Results?

The therapeutic effects of Afobazole typically begin to emerge between the 5th and 7th day of treatment, with the most significant benefits appearing by the end of the 4th week.

These effects may last for 1-2 weeks even after the completion of the treatment course.


What Does Afobazole Contain?

Each tablet of Afobazole contains:

  • Active Ingredient: Fabomotizole dihydrochloride – 10 mg.
  • Inactive Ingredients: Potato starch, microcrystalline cellulose, lactose monohydrate, povidone K-25, and magnesium stearate.


How Should You Take Afobazole?

Afobazole is taken orally after meals.

The recommended dosage is 10 mg per dose, with a total daily intake of 30 mg divided into three doses.

Treatment typically lasts between 2 and 4 weeks.

In some cases, under medical supervision, the dosage can be increased to 60 mg per day, and the duration of treatment extended to up to 3 months.


Are There Any Side Effects?

Afobazole is generally well-tolerated.

However, some users might experience allergic reactions or headaches, which usually resolve without discontinuing the medication.


What Should You Know About Overdosing?

In case of an overdose, symptoms may include increased drowsiness without muscle relaxation.

Emergency treatment may involve the administration of caffeine, usually through a 20% solution administered subcutaneously.


How Should You Store Afobazole?

Store Afobazole in a dry place at temperatures not exceeding 25°C (77°F), away from children.

The medication has a shelf life of 3 years.

Do not use it after the expiration date indicated on the package.

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