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Thymalin® 10 mg x 10 amps. (Lyophilized powder for injection)


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The instruction for medical use of medicine Thymalinum the Trade name Thymalinum the International unlicensed name Is not present the Dosage form Lyophilisate for preparation of solution for injections, Structure 1 bottle active agent – the dry purified extract of a thymus gland (thymus) of cattle of 10 mg, excipient – glycine of 20 mg contains 10 mg. Description Amorphous powder or porous mass of color, white or white with yellowish shade. Pharmacotherapeutic group Immunomodulators. Immunostimulators. Other immunostimulators the ATX L03AX Code the Pharmacological Pharmacokinetics In Details properties it is not described. It is effective at parenteral use. At oral introduction it is quickly inactivated in digestive tract. The pharmacodynamics Regulates quantity and a ratio of T – and V-lymphocytes and their subpopulations, stimulates reactions of cell-mediated immunity, strengthens phagocytosis, stimulates processes of regeneration and a hemopoiesis in case of their oppression and also improves a course of processes of cellular metabolism. Indications as a part of complex treatment of the diseases which are followed by decrease in cell-mediated immunity: – acute and chronic pyoinflammatory diseases of bones and soft tissues – disturbance of regenerator processes (bone fractures, burns, frostbites, a trophic ulcer, beam necrosis of fabrics, a peptic ulcer of a stomach and a 12-perstny gut) – acute and persistent bacterial and viral infections, the multiple sclerosis obliterating atherosclerosis, a pseudorheumatism – oppression of immunity and a hemopoiesis after performing radiation therapy or chemotherapy, when using high doses of antibiotics the Route of administration and doses Before use contents of a bottle dissolve 0.9% of solution of sodium of chloride in 1-2 ml and mix contents easy stirring, without allowing foaming, before receiving a uniform suspension. Timalina appoints the scheme of dosing only the clinical immunologist on the basis of clinical and laboratory inspection of the patient. Enter intramusculary deeply (avoiding hit in blood vessels) daily in the following doses: to adults and children 14 years on 5-20 mg (30-100 mg on a course), to children aged till 1 year – on 1 mg, 1-3 years – on 1-2 mg, from 4 to 6 years – 2-3 mg, from 7 to 14 years – 3-5 mg are more senior. Course of treatment: from 3 to 10 days depending on expressiveness of disturbances of immunity. If necessary carry out a repeated course of treatment in 1-6 months. Side effects Are possible – allergic reactions, skin rashes, hyperaemia, itching of skin – reaction in the injection site of the Contraindication – hypersensitivity to drug components – autoimmune and allergic diseases – pregnancy and the period of a lactation Overdose Strengthening of side reactions. In experiments on animals at chronic introduction in high doses causes involution of a thymus gland. Medicinal interactions It is compatible to biostimulants and immunoperformance-enhancing drugs, rifampicin, an isoniazid. It is necessary to avoid simultaneous use of Thymalinum and T-activin, a timaktid, a timogen or a timoptin which have the similar mechanism of action. The special instructions Treatment by Thymalinum it is necessary to appoint and hold only after inspection and consultations of the immunologist at regular control of immunological indicators. Thymalinum can exponentiate allergic reactions to other medicines at their simultaneous use. To use only the recommended solvent. Not to mix the prepared solution with other medicines. To apply right after preparation. Use in pediatrics is Used only according to purpose and under control of the doctor at the proved existence of disturbances (oppression) of cell-mediated immunity. Features of influence of medicine on ability to run vehicles or potentially dangerous mechanisms Data on influence of medicine on ability to run vehicles or potentially dangerous mechanisms are absent. Form of release and packing On 30 mg in the glass bottles of 2 ml corked with traffic jams brombutilovy rubber for freeze drying, which are pressed out by caps aluminum. On bottles paste the label on a sticky basis. On 5 bottles put in blister strip packaging from a PVC film which becomes covered with aluminum foil. On the 2nd blister strip packagings together with the instruction for medical use in the state and Russian languages put in a pack from cardboard bandbox. Packs put in a group container and paste the label group. To Store storage conditions in original packing for protection against effect of light at a temperature not over 25 about S. Hranit out of children’s reach! 3 years not to apply a period of storage after an expiration date.


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