FREE Shippingto US, AU, UK and EU on all orders over $149


  • New Arrivals
  • Sale
  • Hot items

Oftan® Catachrom Eye Drops 10 ml




1ml solution contains

  • Active ingredients: Cytochrome C 0.675 mg/ml, Adenosine 2 mg/ml, Nicotinamide 20 mg/ml,
  • Excipients: benzalkonium chloride, sodium succinate hexahydrate, sorbitol, sodium dihydrogen phosphate dihydrate, sodium hydrogen phosphate dihydrate, water for injection.


Pharmacological properties


When applied topically, Cytochrome C is not absorbed into the blood. Adenosine passes freely through the cornea and is distributed to all tissues. The half-life of adenosine from blood plasma is less than one minute, it is metabolized in almost all tissues with the formation of inosine, xanthine and urate, which are freely excreted in the urine. Ribose, which is a constituent element of adenosine, is metabolized to glyceraldehyde-3-phosphate, then to pyruvate and burns out in the Krebs cycle. Nicotinamide is rapidly absorbed and partially metabolized to nicotinic acid. Both of these compounds are metabolized to N-methylnicotinamide, which is further broken down in the liver. Metabolites and unchanged nicotinamide are excreted in the urine.



Oftan ®  Katahrom is a combined preparation, the mechanism of action of which is primarily based on the antioxidant and metabolism-improving and trophic effects of the eye tissues of the active components that make up its composition – cytochrome C, adenosine and nicotinamide.

Cytochrome Cis a high molecular weight iron porphyrin compound, similar in structure to hemoglobin, consists of heme and a single peptide chain (apocytochrome C). Cytochrome C plays an important role in biochemical redox processes. It has a high chemical activity in relation to the utilization of oxygen radicals. Inhibition of oxidative processes in all tissues anterior to the lens (cornea and intraocular fluid) is of great importance for suppressing the development of cataracts, since ultraviolet radiation causes chain reactions in these tissues with the formation of radicals that can lead to clouding of the lens. Cytochrome C, which is part of Oftanâ Katahrom eye drops, has the ability to neutralize oxygen radicals in certain redox states and,

Adenosine is a necessary component for the repair of DNA and RNA, as well as a structural element of these molecules. Adenosine is involved in the processes of energy metabolism. Adenosine is the main element of DNA repair in the lens epithelium, which is necessary to repair damage caused, for example, by the damaging effects of oxidation. Due to its vasodilating action and increased ocular blood supply, adenosine helps flush out toxic decay products, stimulating the production and exchange of intraocular fluid. Adenosine reduces inflammation in the conjunctiva, cornea, and other eye tissues.

Nicotinamide is a structural element of NAD and NADP. Promotes the regeneration of endothelial cells of the lens, which helps prevent cataracts.


Indications for use

  • Cataract


Dosage and administration

Locally, 1-2 drops in the conjunctival sac of the affected eye 3 times a day.

The course of treatment is determined by the attending physician.


Side effects

– short-term burning and stinging of the eyes

– contact dermatitis


– nausea

– arterial hypotension, dizziness

– shortness of breath

Nicotinic acid has a vasodilating effect and can cause:

– hot flashes

– sensation of heat

– fainting

– sensation of pulsation in the temples



– hypersensitivity to the components of the drug

– pregnancy and lactation

– children and adolescents under the age of 18


Drug Interactions

There were no clinically significant interactions with other drugs.


Special instructions

Oftan Katahrom eye drops are not intended for the treatment of glaucoma. Oftanâ Katahrom contains benzalkonium chloride as a preservative and is not recommended for use when wearing contact lenses. Before using the drug, remove contact lenses and re-install them no earlier than 15 minutes later. Benzalkonium chloride may cause transient eye irritation.

Pregnancy and lactation

Since the safety and efficacy of Oftan Katahrom eye drops during pregnancy and lactation have not been studied, the use of the drug is not recommended.

Application in pediatrics 

The safety and efficacy of Oftanâ Catachrom eye drops in children have not been evaluated in appropriate and well-controlled studies, so the use of the drug in children and adolescents under 18 years of age is not recommended.

Features influence on the ability to drive vehicles and potentially dangerous mechanisms

The drug does not affect the ability to drive a car or use mechanical equipment. As with all ophthalmic preparations, if transient blurred vision is noted, the patient should wait until vision is restored before driving or using mechanical equipment.



Symptoms: not reported

Treatment: symptomatic


Storage conditions

Store at + 8 – +15 °С

Keep out of the reach of children!

Shelf life – 3 years

After opening the vial – 1 month.

Do not use the drug after the expiration date indicated on the package.

Additional information



There are no reviews yet.

Be the first to review “Oftan® Catachrom Eye Drops 10 ml”

Your email address will not be published. Required fields are marked *