The instruction for medical use
of DERMAZOLTM medicine
the Trade name
the International unlicensed
name Ketokonazol Lekarstvennaya a form
Cream of 2% 15 g and 30 g
of 1 g of cream contains
active agent – ketokonazol 20 mg,
excipients: propylene glycol, alcohol ketostearyl, a ketomacrogoal 1000, paraffin white soft, paraffin light liquid, EDTA dinatrium, polysorbate 80, sodium sulfite anhydrous, the water purified.
Uniform cream of white color
Antifungal drugs for treatment of diseases of skin. Antifungal drugs for topical administration. Imidazole derivatives. Ketokonazol
ATX D01AC08 Code
Pharmacokinetics properties. At external use is practically not exposed to a resorption. Prolonged use in the form of 2% of cream does not lead to accumulation of a ketokonazol in blood.
Pharmacodynamics Antifungal means derivative of an imidazoldioksolan. Ketokonazol has antifungal effect, specifically blocks synthesis of ergosterol of a cellular membrane of mushrooms. It is active concerning dermatophytes: Trichophyton spp., Epidermophyton floccosum, Microsporum spp., barmy and yeast-like mushrooms: Candida spp., Pityrosporum ovale.
Treatment of fungal infections of skin and the nails caused by sensitive microorganisms
– a dermatomycosis of smooth skin
– an epidermophitia of brushes and feet
– an inguinal epidermophitia
– skin candidiasis
– a chromophytosis
– seborrheal dermatitis
the Route of administration and doses
In skin candidiasis, a dermatomycosis of skin, an epidermophitia of hands and legs, an inguinal epidermophitia and a chromophytosis is recommended to apply DermazolTM cream on the struck surface of skin once a day.
In seborrheal dermatitis DermazolTM cream is applied on an affected area by 1 or 2 times a day, depending on disease severity. Treatment needs to be continued during several days after disappearance of all symptoms of a disease or before obtaining negative takes of a mycologic research. The diagnosis should be revised if after 4 weeks of treatment there is no improvement.
A usual course of treatment of a dermatofitiya of feet of 2-6 weeks (an inguinal epidermophitia – 2-4 weeks), candidiases – 2-3 weeks, a chromophytosis – 2-3 weeks.
– the burning sensation, an erythema, an itching in the site of application
– the increased fat content/xeroderma (especially in the first days of treatment)
– hypersensitivity (irritation, a parasthesia in the site of application,
contact dermatitis, peeling of skin, violent rash)
Is very rare
– a small tortoiseshell
of the Contraindication
– hypersensitivity to drug components
At use of cream along with local glucocorticosteroids (GKS) or right after their prolonged use it is necessary to apply GKS in the morning (with gradual cancellation in case of need), and DermazolTM cream in the evening.
instructions Cream it is applied only outwardly. At hit in eyes it is necessary to wash them with water carefully.
Pregnancy and the period of a lactation
Due to the insufficient experience of use in this group cream need to be applied with care.
The feature of influence of medicine on ability to run the vehicle or potentially dangerous
Ketokonazol mechanisms does not affect ability to run the vehicle or potentially dangerous mechanisms
Symptoms: an erythema, hypostasis, burning in the site of application
Treatment: drug withdrawal, symptomatic therapy
the Form of release and packing
On 15 g or 30 g of drug place in the aluminum or laminated tuba with the screw-on plastic cover.
On 1 tuba together with the instruction for medical use in the state and Russian languages place in a cardboard box.
To Store storage conditions in the dry, protected from light place at a temperature not above 25ºС.
To store out of children’s reach!
not to apply a period of storage after expiry date!
the Producer Kusum Heltker Pvt.
Ltd., JV 289 (A), Riiko Indl. Chopanki’s Area, Bkhivadi (Raj.), India
Owner of the registration certificate
Kusum Heltker Pvt. Ltd., India
the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods) Representative office of Kusum Heltker Pvt. Ltd. Association, India in RKg. Almaty, Dostyk Ave., 117/6, BC Khan Tengri. Phone number: 295-26-50, 295-26-51 (54), Fax: 295-26-55 e-mail address: Office@kusumhealthcare.kz