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Acyclovir Santo 5% ointment 5 grams of a tube outward.

$3.20

d1379352a9bd

Description

The instruction for medical use of medicine Santo’s Acyclovir the Trade name Santo’s Acyclovir the International unlicensed name Acyclovir Dosage Form Ointment for external use of 5% Structure of 100 g of drug is contained: active agent – acyclovir – 5.00 g, excipients: propylene glycol, vaseline, liquid paraffin, wax emulsion, a macrogoal (polyethylene oxide 1500), the water purified. Description Ointment of white or almost white color. Existence of a characteristic smell is allowed. Pharmacotherapeutic group Antiviral drugs. Acyclovir. ATH code: D06BB03 the Pharmacological Pharmacokinetics At properties use of drug in the recommended doses system absorption minimum. The pharmacodynamics Acyclovir is antiviral medicine. In pilot studies of in vitro shows activity against a virus of a herpes simplex (herpes simplex) 1 and 2 of type. At hit in the cells infected with a herpes virus, acyclovir it is phosphorylated and will be transformed to an active form – acyclovir triphosphate. The first stage of this process depends on existence of the HSV coded thymidinekinase. Acyclovir triphosphate works as inhibitor and substrate for herpes – specific DNA of a polymerase, preventing further synthesis of virus DNA, not influencing usual cellular processes. Indications – the skin infections caused by the Herpes simplex virus of types 1 and 2 including idle time (including lips) and recurrent genital herpes. Route of administration and doses Outwardly. Drug is applied with clean hands or a cotton plug of 5 times a day (each 4 hours) a thin layer on the sites of skin struck and adjoining on them. For achievement of the maximum therapeutic effect it is necessary to use drug already at the first symptoms of a disease (burning, an itching, pricking, feeling of tension and reddening). However, treatment can be begun also at later stage (existence of a papule or vesicle). Therapy should be continued till that time while on bubbles the crust is not formed or until they completely begin to live. Duration of treatment averages 5 days. In case of lack of healing the treatment can be continued up to 10 days. In the absence of effect it is necessary to see a doctor. Side effects Side reactions are specified with use of the following system of classification of undesirable effects by frequency: very often & gt, 1/10, is frequent ≥1/100 and ˂1/10, infrequently ≥1/1000 and ˂1/100, is rare ≥1/10,000 and ˂1/1000, is very rare ˂1/10,000. Disturbances from skin and hypodermic cellulose: Infrequently: – the taking place burning or pricking after drug use – dryness or peeling of skin – naggers Redko: – an erythema – contact dermatitis in the site of application of Disturbance from the immune system: Very seldom: – reactions of immediate hypersensitivity, including a Quincke’s edema and urticaria in case of the side reactions including which are not specified in the instruction for use it is necessary to stop use of medicine and to see a doctor. Contraindications – hypersensitivity to acyclovir, a valatsiklovir, propylene glycol and other components of drug. Medicinal interactions At external use the interaction with other medicines is not revealed. The special instructions Drug are not recommended to be applied on mucous membranes of an oral cavity and eyes as development of the significant local inflammation is possible. At treatment of genital herpes it is necessary to avoid sexual contacts or to use condoms as use of acyclovir does not prevent transfer of a virus to partners. To avoid accidental hit in eyes. At patients with the weakened immunity (for example, at HIV-positive patients or recipients of marrow) use of oral forms of acyclovir is recommended. In case of need treatments of any infection it is necessary to consult such patients with the doctor. Drug contains propylene glycol which can cause irritation of skin. Pregnancy and the period of a lactation Use of drug is shown only when the expected advantage for mother exceeds potential risk for a fruit. When prescribing acyclovir in forms for system use medicine gets into breast milk. However, it is expected that the dose received by the child who is on breastfeeding is small. Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms it is not applicable. Overdose At accidental ingestion or topical administration of all packing containing 10 g of ointment of 500 mg of acyclovir an adverse effect was not revealed. However emergence gastrointestinal (nausea and vomiting) and neurologic effects (headache and confusion of consciousness) as a result of accidental repeated overdose at intake of acyclovir inside within several days is described. Acyclovir is removed at a hemodialysis. A form of release and packing Ointment for external use of 5%. On 5 g of drug place in a tuba aluminum. Each tuba together with the instruction for medical use in the state and Russian languages is put in a pack from cardboard. Storage conditions In the dry, protected from light place at a temperature not above 25 °C. To store out of children’s reach. Expiration date 3 years. Not to apply after an expiration date. Prescription status Without prescription. Name and country of the JSC AKRIKHIN manufacturing organization, Russia 142450, Moscow region, Noginsk district. Old Kupavna, Kirov St., 29. Phone number / fax: +7 (495) 702-95-03. The name and the country of the owner of the registration certificate of JSC Khimpharm, the Republic of Kazakhstan the Name and the country of the JSC AKRIKHIN organization packer, Russia the Address of the organization accepting in the territory of the Republic of Kazakhstan a claim (offer) from consumers on quality of medicine of JSC Khimpharm, Shymkent, Republic of Kazakhstan, Rashidov St., 81 the Address of the organization in the territory of the Republic of Kazakhstan responsible for post-registration observation of safety medicinal sredstvaao Khimpharm, Republic of Kazakhstan, Shymkent, Rashidov St., 81

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