Cold and Flu / Cough

Percol 30 mg (50 tablets)

Brands: Marion Biotech (India)

$10.20

Quantity

Percol 30 mg (50 tablets) quantity

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d16fdf66e347

Brands:: Marion Biotech (India)

Description

Instruction for medical use

of Perkolit Torgovoye medicine name
of Perkolit

International unlicensed

name Ambroxol Dosage Form

of the Tablet Ingredients:
One tablet contains
active agent: Ambroxol hydrochloride of 30 mg
excipients: microcrystalline cellulose, starch corn, the talc purified magnesium stearate, aerosil.

The description
of the Tablet of white color, round shape, from a biconvex surface, with risky on one party.

Pharmacotherapeutic group
Drugs for elimination of symptoms of cold and cough. Expectorant drugs. Mucolytics. Ambroxol.
The code of automatic telephone exchange R05CB06

the Pharmacological

Pharmacokinetics Later properties of intake of Ambroxol a hydrochloride is quickly and completely absorbed from a GIT. Well gets into tissues of lungs. The maximum concentration of Ambroxol in blood plasma is observed in 1/2–3 hours after oral administration. Therapeutic action develops in 30 minutes and lasts from 6 to 12 hours (depending on the accepted dose). Elimination half-life – 10–12 hours. Cumulation of drug is not observed. Extent of linking with proteins of blood plasma – about 90%. After intake quickly gets into all bodies and fabrics, but the highest concentration of drug is noted in tissues of lungs. Well gets through GEB, a placental barrier, cosecretes with breast milk. Metabolism of Ambroxol happens in a liver by conjugation to formation of inactive metabolites (glucuronides and dibromoantranilovy acid). 90% of drug are removed with urine.

The Ambroxol pharmacodynamics a hydrochloride – synthetic sekretolitichesky and sekretomotorny means of group of benzylamines. Drug has promoting effect of rather serous cells of glands of a mucous membrane of bronchial tubes that leads to increase in secretion of slime and change of a ratio of serous and mucous components of a phlegm. Simultaneous activation of hydrolytic enzymes and increase in physical activity of a ciliary epithelium of bronchial tubes causes department of a pathological secret from walls of bronchial tubes and improves its removal from airways, restoring drainage function of small bronchial tubes and bronchioles. Drug increases surfactant content in lungs and also prevents its destruction in pnevmotsita. It leads to normalization of rheological indicators of a phlegm, reduces its viscosity and adhesive properties. Ambroxol the hydrochloride directly stimulates activity of a ciliary epithelium of bronchial tubes, prevents its adhesion and improves mukotsiliarny evacuation of a phlegm. Drug reduces hyperreactivity of muscles of bronchial tubes of patients with bronchial asthma. Has mild antibechic action. Ambroxol has anti-inflammatory effect, shows antioxidant properties, stimulates local immunity

Indications

sekretolitichesky therapy of the acute and chronic bronchopulmonary diseases which are characterized by disturbance of secretion and the complicated phlegm otkhozhdeniye

the Route of administration and doses
of Perkolit of a pill are taken inside after a meal with enough warm liquid.
Adults and children since 12 years on 1 tablet 2 times a day, the maximum dose of 3 tablets in day.
The course of treatment makes 4-5 days.

Side effects
Often

– dyspepsia, nausea, heartburn, diarrhea
Seldom
– allergic reactions (skin rash, an itching)
– a Quincke’s disease
Are possible
– hypersalivation
– increase in secretion mucous a nose
–

the Contraindication hyperthermia
– hypersensitivity to Ambroxol to a hydrochloride and/or to other components of drug
– a peptic ulcer of a stomach and duodenum
– the I trimester of pregnancy and the period of a lactation
– the children’s age up to 12 years

Medicinal interactions
is not recommended to appoint Perkolit along with antibechic drugs which oppress removal of a phlegm. Drug increases therapeutic effectiveness of doxycycline, a tsefuroksim and amoxicillin. Ambroxol the hydrochloride increases concentration of rifampicin in lungs. Use of drug with cardiac glycosides, diuretics is possible, the hydrochloride Ambroxol combination with theophylline therapeutic is reasonable.

Special instructions
At restriction of functional capacity of kidneys and/or in a serious illness of a liver of Perkolit need to be applied with extra care, reducing the applied dose and increasing time between administrations of drug.
Pregnancy and the period of a lactation
In spite of the fact that there are no reliable data of negative influence of Perkolit on a fruit and babies, Perkolit’s use in II and III trimesters of pregnancy and in the period of a lactation perhaps after the careful analysis of a ratio advantage/risk the attending physician so far.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms

the Overdose Symptoms does not influence: excitement, vomiting, the raised sialosis, diarrhea, dyspepsia. Treatment: simpomatichesky therapy.
The form of release and packing
On 10 tablets place in blister strip packagings from aluminum foil. On 5 planimetric packs together with the instruction for use in the state and Russian languages put in a pack from cardboard.
Storage conditions
Drug should be stored in the dry, protected from light place at a temperature not over 30 about S.
Hranit out of children’s reach!

4 years
not to use a period of storage after expiry date!

Prescription status
Without prescription

Marion Biotek Pvt.Ltd. Producer
B-49, Sector-67, Noiade, India

Owner of the registration certificate
Marion Biotek Pvt.Ltd., India

Additional information