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NYSTATIN 250,000 IU (20 coated tablets)




The instruction for medical use

of medicine


the Trade name


the International unlicensed

name Nystatin Dosage Form

of the Tablet, coated, 250,000 PIECES and 500,000 PIECES


One tablet contains

active agent: nystatin of 55.5 mg (250,000 PIECES) or 111 mg (500,000 PIECES)

excipients: lactoses monohydrate (sugar milk), magnesium hydroxycarbonate (magnesium carbonate the main), gipromelloz (oksipropilmetiltsellyuloz), stearate calcium monohydrate, potato starch

cover excipients: lactoses monohydrate (sugar milk), a gipromelloz (oksipropilmetiltsellyuloz), the titan dioxide (E171), polysorbate-80 (twin-80), talc, vanillin, dye quinolinic yellow (E 104), dye tropeolin About

the Description

of the Tablet, film coated, light yellow color with a greenish shade, with a light smell of vanillin

Pharmacotherapeutic group

Intestinal antimicrobial and anti-inflammatory drugs. Antibacterial drugs. Nystatin.

The ATX A07AA02 code

the Pharmacological

Pharmacokinetics Drug properties is badly soaked up from digestive tract. The bulk of the drug taken inside is allocated with a stake. Nystatin has no cumulative properties.

A pharmacodynamics

the Half-yen antifungal antibiotic highly active concerning yeast-like mushrooms of the sort Candida. In structure of an antibiotic there are double bonds possessing a high tropnost to styrene structures of a cytoplasmic membrane of mushrooms that promotes embedding of a molecule of drug in a cell membrane and to formation of a large number of channels via which uncontrolled transport of electrolytes is carried out, increase in osmolarity in a cell leads to her death. The resistance develops very slowly.


– candidiasis of mucous membranes of skin and internals

– prevention of fungal complications at long-term treatment by antibiotics, especially at the exhausted and weakened patients

the Route of administration and doses

apply Nystatin To treatment of candidiasis of internals inside irrespective of meal.

The adult appoint 111 mg (500,000 PIECES) 34 times or on 55.5 mg (250,000 PIECES) of 68 times a day. In generalized candidiasis the daily dose can be increased up to 6,000,000 PIECES.

Duration of a course of treatment is 10 14 days. If necessary in a week the course can be repeated.

Side effects

– nausea, vomiting, diarrhea, an abdominal pain

– a fever, a hyperthermia

– a skin itching, allergic reactions

In these cases reduce a dose or cancel drug.


– hypersensitivity

– an abnormal liver function, pancreatitis

– a peptic ulcer of a stomach and duodenum

– pregnancy

– children’s age up to 18 years

Medicinal interactions

At simultaneous use of Nystatin with Clotrimazolum the activity of the last decreases.

Special instructions

In fungus diseases of a vagina the simultaneous treatment of the sexual partner is recommended.

Use at pregnancy and in the period of a lactation

At pregnancy drug is contraindicated. In the period of a lactation apply only if the expected advantage for mother exceeds potential risk for the child.

Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms

Use of drug does not affect ability of control of vehicles and occupations other potentially dangerous types of activity demanding the increased concentration of attention and speed of psychomotor reactions.

A form of release and packing

On 10 tablets in blister strip packaging from a film of the polyvinylchloride and printing aluminum foil varnished or papers with a polyethylene covering.

On the 2nd blister strip packagings together with the instruction for medical use in the state and Russian languages place in a pack from cardboard.

To Store storage conditions in the dry, protected from light place at a temperature not higher than 25 wasps.

To store out of children’s reach!

2 years

not to use a period of storage after an expiration date.

Prescription status

According to the prescription

JSC Biosintez Producer,

Russia 440033, Penza, Druzhby St., 4, ph. / fax (8412) 57-72-49,


the Name and the country of the owner of the registration certificate

of JSC Biosintez, Russia

the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods)

of JSC Biosintez,

Russia 440033, Penza, Druzhby St., 4, ph. / fax (8412) 57-72-49,


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