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MEXIDOL® (Emoxipine) 125 mg, 50 coated tablets
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Description
Compound
1 tablet contains active ingredients:
- Passionflower – 150 mg
- Hawthorn – 150 mg
- Melissa – 100 mg
- Magnesium lactate dehydrate – 150 mg
- Pyridoxine hydrochloride (Vitamin B6) – 3 mg
Pharmachologic effect
The action of the drug is provided by the combined action of its constituent components, therefore, kinetic observations are not possible.
Passion flower extract contains alkaloids and a flavanoid – vitexin, has a mild sedative effect on the central nervous system, promotes sleep recovery, reduces anxiety and nervousness, has an antispasmodic effect on smooth muscles, improves heart function, and has a sedative effect.
Hawthorn extract contains flavonoids, choline, acetylcholine, tannins, phytoserines, etc. Due to the presence of triterpene compounds and flavonoids, it has an antispasmodic effect, selectively expanding the vessels of the heart and brain; hypotensive effect; contributes to the normalization of venous pressure, improves the function of the vascular walls. It has a mild sedative effect.
Lemon balm extract contains 0.1-0.3% essential oil, the main components of which are citronellal, geraniol, citral, citronellol, linalool, phenylpropanoids, chloragenic and caffeic acids. This sedative has anxiolytic, antidepressant, antispasmodic, immunomodulatory, antiviral, antiallergic and antimicrobial properties. A wide range of therapeutic effects of lemon balm preparations is due to the content of various biologically active substances shown above: a pronounced sedative effect – citronellal, antispasmodic properties – geraniol and citronellol, phenylpropanoids (rosemary, coffee, chlorogenic and other hydroxycinnamic acids) should be considered as responsible for antiviral, immunomodulatory antihistamine, antioxidant and antimicrobial properties. The plant is recommended as an antiemetic for pregnant women, a diuretic and an appetite enhancer.
Magnesium is an inorganic element that is present in all cells of the body in its normal state. Magnesium is an essential element for cell life and is involved in most metabolic reactions. From a physiological point of view, magnesium is a cation of predominant intracellular localization. Magnesium ions reduce the excitability of neurons, play an important physiological role in maintaining the ionic balance in muscles, slow down neuromuscular transmission, and participate in many enzymatic reactions. Magnesium deficiency in the body is manifested by muscle weakness, tremors, tetany, ataxia, increased reflex excitability, irritability, sleep disorders, heart rhythm disturbances with extrasystoles or tachycardia, disorders of the digestive tract with diarrhea. Deficiency can be primary due to congenital impairment of magnesium metabolism and secondary due to lack of intake, as well as due to poor gastrointestinal absorption, excessive renal excretion and with an increase in the need for magnesium (with increased physical and mental stress, stress, pregnancy).
Pyridoxine (vitamin B6) as a coenzyme is involved in many metabolic processes, in the regulation of the metabolism of the nervous system. Promotes faster absorption of magnesium from the gastrointestinal tract, penetration and retention of magnesium in cells.
Indications
- Increased nervous irritability;
- nervous tension;
- irritability;
- feeling anxious and depressed;
- functional manifestations of anxiety attacks with hyperventilation;
- increased fatigue;
- heart palpitations;
- sleep disturbance, insomnia, depressive conditions;
- pain and muscle spasms, gastrointestinal cramps.
Contraindications
Hypersensitivity to the components of the drug. Childhood.
Method of administration and dosage
When used freely by the consumer, it is necessary to comply with the norms that are written on the packaging. If the drug is prescribed by a doctor, a change in dosage is possible. Usually 1 tablet is prescribed 2-3 times a day.
The maximum daily dose is 3 tablets. For sleep disorders and insomnia, the dose of the drug is 2 tablets half an hour before bedtime. Novarest is taken orally with plenty of water.
Application during pregnancy and lactation
Since biologically active food additives are freely used by the consumer, Novarest is not advised to be used by pregnant women without the knowledge of a doctor. The doctor, having determined the need of a pregnant woman for a similar drug, may prescribe Novarest.
Side effects
Novorest is usually well tolerated.
Rarely: allergic reactions, weakness.
Special instructions
The duration of the use of the drug Novorest is not limited. Withdrawal of the drug does not develop withdrawal syndrome.
When using the drug, it is recommended to refrain from drinking alcohol.
Drug interactions
Novarest enhances the action of cardiac glycosides, tranquilizers, substances that have a depressing effect on the central nervous system, as well as alcohol.
Overdose
Symptoms: dizziness, abdominal cramping, chest tightness, dilated pupils, nausea, vomiting.
Treatment: gastric lavage is possible, symptomatic therapy if necessary.
Storage conditions
Store in a dry, dark place and out of reach of children at a temperature not exceeding 25 ° C.
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