The instruction for medical use
the Trade name
the International unlicensed
name Naphazoline Dosage Form Spray of Nasal 0.05% and 0.1% 10 Ml, 20 ml
of 1 l of drug contain
active agent – naphazoline of nitrate of 0.5 g, 1.0 g
excipients – the boric acid, water purified.
Transparent, colourless liquid
of Antikongestanta and other nasal drugs for topical treatment. Sympathomimetics
the ATX R01AA08 Code
Pharmacokinetics Later properties of drawing on mucous membranes is quickly soaked up. Possesses resorptive action.
Alpha adrenomimetik. Naphazoline possesses the significant vasoconstrictive action. Naphazoline stimulates alfa2-adrenoceptors that leads to narrowing of peripheral blood vessels, increases arterial blood pressure, expands pupils. Owing to vasoconstrictive action drug reduces puffiness, hyperaemia, exudation.
– acute rhinitis
– allergic rhinitis
– acute and chronic laryngitis
– a laryngeal edema of allergic genesis
– hyperaemia and puffiness of mucous membranes of upper airways
– a rinoskopiya
the Route of administration and doses
Spray for a nose
of Adult 0.1% and 0.05% 1 injection in each nasal course 1-2 times 2 put a laryngeal edema against the background of radiation.
To children of 0.05% of 2 years up to 6 years on 1 injection, from 6 to 15 years on 1 injection in each nasal course 1-2 times a day. In hypostasis of phonatory bands to enter 1-2 ml of solution in the form of spray or small doses the guttural syringe
As supportive application at surface anesthesia on 2-4 drops on 1 ml of local anesthetic.
Course of treatment of 5-6 days.
– a headache
– increase in arterial blood pressure, tachycardia
– irritation and a reactive hyperemia of a mucous membrane
– hypostasis of a mucous membrane (at use more than 1 week), atrophic
of the Contraindication
– children’s age up to 2 years (for 0.05% of solution)
– children’s age up to 12 years (for 0.1% of solution)
– an arterial hypertension, tachycardia, the profound atherosclerosis
– a serious illness of eyes
– a hyper thyroidism
– chronic rhinitis
– hypersensitivity to drug components.
– the concomitant use of MAO inhibitors (antidepressants) and the period up to 14 days after the end of their use
– closed-angle glaucoma
should not be applied along with MAO inhibitors or within 10 days after the end of their use. Slows down absorption of mestnoanesteziruyushchy HP (extends their action when carrying out surface anesthesia).
Can have resorptive effect.
At prolonged use the expressiveness of vasoconstrictive action gradually decreases. At prolonged use it is possibletolerance.
It is not recommended to apply it is long drug without consultation of the doctor.
Pregnancy and the period of a lactation
Use of drug at pregnancy and in the period of a lactation perhaps only according to strict indications when the expected therapeutic effect for mother exceeds potential risk of development of side effects at a fruit or the child.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
Considering side effects of drug it is necessary to be careful at control of motor transport or potentially dangerous mechanisms
Symptoms – decrease in body temperature, bradycardia, arterial hypertension
Treatment – symptomatic
the Form of release and packing
Spray: 0.05% and 0.1% solution on 10 ml, 20 ml in bottles.
On 10 ml and 20 ml in polyethylene bottles of high density with a cover the spray and a protective cap Bottles together with the corresponding number of instructions for use in the state and Russian languages stack in boxes cardboard, placing between laying bottles from cardboard
to Store in the place protected from light, at a temperature not over 30 s.
To store out of children’s reach!
A period of storage
After an expiration date medicine should not be applied.
the Name and the address of the producer:
Pharmation LLP 2010, Republic of Kazakhstan, 100019, Karaganda, Chkalov St. 7, ph. fax (7212) 42-67-34
Name and country of the owner of the registration certificate
of Pharmation LLP 2010, Kazakhstan
Name and country
of Pharmation LLP organization packer 2010, Kazakhstan