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Muskomed 0.25% 30g cream

$26.30

201d9743422e

Description

The instruction for medical use of MUSKOMED medicine danny medicine is subject to additional monitoring. It will allow to reveal new information on safety quickly. We appeal to health care providers to report about any suspected undesirable reactions. A trade name Muskomed Mezhdunarodnoye the unlicensed name Tiokolkhikozid Lekarstvennaya the form Cream for external use of 0.25%, 30 g the Description Uniform cream of the light yellow Structure of 1 G of Cream color contains active agent – a tiokolkhikozid of 2.5 mg, excipients: lindens essence, sodium alginate, sodium lauryl sulfate, polysorbate 80, lanolin the hydrogenated, cetyl alcohol, wax cetylradio, stearic acid, methylparahydroxybenzoate, ethylparahydroxybenzoate, water purified. Pharmacotherapeutic group Drugs for treatment of diseases of a musculoskeletal system. Muscle relaxants. Muscle relaxants of the central action. Muscle relaxants of the central action others. Tiokolkhikozid. The ATX M03BX05 code the Pharmacological Pharmacokinetics At properties topical administration practically does not get into a system blood stream. About 70% of active agent are localized on the site of putting drug. Linking with proteins (generally with albumine) makes 13%. Tiokolkhikozid and his metabolites are removed mainly with excrements. The pharmacodynamics Muskomed as active agent contains tiokolkhikozid, the semi-synthetic muscle relaxant received from a natural glycoside of a kolkhikozid. Shows selection affinity to piperidic acid (GAMK) and glycine receptors that causes effect of drug at various levels of nervous system, both at spasms of local character, and at spasms of the central origin. Moderately reduces or eliminates the muscular spasms caused by influence from the central nervous system. In a spastic muscular hypertension reduces the passive resistance of muscles on stretching or reduces painful involuntary muscular spasms. Muskomed has no kurarepodobny effect, does not cause paralysis and does not influence cardiovascular and respiratory systems. Indications – symptomatic treatment of painful muscular spasms the Route of administration and doses Muskomed apply cream outwardly. At adults and teenagers of 18 years Muskomed cream is applied by 2-3 times a day under control of the attending physician. The strip of cream is applied to skin and slightly rubbed. The amount of the used drug depends on the size of a painful zone. After putting drug of a hand it is necessary to wash up. Duration of treatment depends on indications and efficiency of therapy. Side effects classify Side reactions by frequency as follows: very often (& gt, 1/10), it is frequent (& gt, 1/100, & lt, 1/10), infrequently (& gt, 1/1000, & lt, 1/100), is rare (& gt, 1/10000, & lt, 1/1000), is very rare (& lt, 1/10000), with an unknown frequency (on the basis of the available data the frequency cannot be determined). Seldom – contact dermatitis, rash, a small tortoiseshell, bronchial asthma, a Quincke’s disease – dizziness, drowsiness – nausea, vomiting, an abdominal pain, a diarrhea Very seldom – an acute anaphylaxis, allergic skin reactions of the Contraindication – hypersensitivity to drug components – disturbance of integrity of integuments – hypotonia of muscles – slight paralysis – therapy by anticoagulants and predisposition to hemorrhages – pregnancy and the period of a lactation – children’s and teenage age up to 18 years the Medicinal interactions of Data on medicinal interaction are not present. However it is recommended to be careful at a concomitant use with other muscle relaxants. At simultaneous use with the drugs oppressing the central nervous system including with alcohol, antihypertensive drugs, kurarepodobny drugs strengthening of muscle relaxation and oppression of central nervous system, development of hypotonia is possible. At simultaneous use with anticoagulants the risk of bleedings increases. Special instructions in case of development of reactions of hypersensitivity drug treatment should be stopped. Muskomed cream should be applied only to the uninjured skin, avoiding hit on open wounds. After drawing it is not necessary to apply an occlusive bandage. It is not necessary to allow hits of drug in eyes and on mucous membranes. As a part of drug there are etilpilparaben, an ethylparaben, methylparaben. These substances can cause a bronchospasm, a small tortoiseshell, dermatitis, allergic reactions of the slowed-down type are possible. Anhydrous, alcohol cetyl stearyl being a part of drug, reactions can lead lanolin ment local skin (for example, contact dermatitis). Patients have to be informed on potential risk in case of approach of pregnancy and on need to use effective methods of contraception. For timely obtaining new information on safety of doctors and patients ask to report about any expected side reactions. Fertility Tiokolkhikozid and his metabolites in different concentration have ability to cause aneuploidies that can be risk factor of decrease in fertility at the person. Use at pregnancy the Data on use of a tiokolkhikozid for pregnant women are limited. Medicine is contraindicated at pregnancy and at the women of childbearing age who are not using contraception. Use in the period of a lactation Because tiokokhikozid gets into breast milk, its use during feeding by a breast contraindicated. Use in pediatrics Medicine should not be applied at children and teenagers 18 years are younger. The feature influence of medicine on ability to run the vehicle or potentially dangerous mechanisms during treatment needs to be careful at control of motor transport and performance of other potentially dangerous types of activity demanding the increased concentration of attention and speed of psychomotor reactions. Overdose Symptoms: strengthening of side effects is possible. Treatment: symptomatic and maintenance therapy. The form of release and packing On 30 g of drug place in tubas aluminum. On 1 tuba together with the instruction for medical use in the state and Russian languages put in a pack from cardboard. To Store storage conditions at a temperature not above 25 °C. To store out of children’s reach! 3 years not to apply a period of storage after an expiration date. Prescription status According to the prescription the Producer UORLD of ILACh DIGNITY MEDICINE. VE TIDZh. A.Sh., TURKEY (Bagdzhylar Ilchesi, Gyuneshli, Evren Makhallesi, Dzhami Yolu Dzhad. No. 50 K. 1B Zemin 4-5-6, Istanbul) WORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş., TURKEY (Bağcılar İlçesi, Güneşli, Evren Mahallesi, Cami Yolu Cad. No: 50 K. 1B of Zemin 4-5-6, İstanbul). Owner of the registration certificate UORLD of ILACh DIGNITY MEDICINE. VE TIDZh. A.highway., TURKEY the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products: RIN Pharm LLP, RK, Almaty, Suyunbaya Ave., 222 B Ph. / fax: +7 (727) 2529090 Address of the organization responsible for post-registration observation of safety of medicine: TROKA-S PHARMA LLP, RK, Almaty, Suyunbaya Ave., 222 B Cellular ph. +7 701 786 33 98, (24-hour access). e-mail: pvpharma@worldmedicine.kz

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