Diagnostic Aids / Eye Care

Midriatsil 15 ml of 1% eye drops

Brands: Alcon (Belgium)

$27.70

Quantity

Midriatsil 15 ml of 1% eye drops quantity

Add to cart

Add to wishlist

Sku:

4e12fb44a646

Brands:: Alcon (Belgium)

Description

The instruction for medical use

of MIDRIATsIL medicine

the Trade name
Midriatsil

Mezhdunarodnoye the unlicensed

name Tropikamid Lekarstvennaya
the Drop form eye 1%, 15 ml

Structure
of 1 ml contains
active agent – tropikamid 10.0 mg,
excipients: a benzalkoniya chloride of 0.1% (preservative), sodium chloride of 7.0 mg, dinatrium edetat 0.1 mg, Acidum hydrochloricum concentrated and/or sodium hydroxide (for adjustment rn), purified water up to 1 ml.

The description
Transparent, colourless solution

Pharmacotherapeutic group
Drugs for treatment of diseases of eyes. Anticholinergics, M – a holinoblokator.
The code of automatic telephone exchange S01FA06

the Pharmacological

Pharmacokinetics Later properties of instillation drug in a conjunctival sac tropikamid in insignificant degree is exposed to system absorption. Owing to absorption of active agent in a blood stream, development of side effects of system character is possible (concern, a condition of excitement, dryness in a mouth, a dysuria, a hyperthermia). System side effects are observed, first of all, at chest and small children and people of advanced age. At use of a tropikamid it is necessary to be careful in a dosage and to consider a possibility of the increased individual sensitivity of patients. To be removed with urine.
A pharmacodynamics
Tropikamid – anticholinergic which effect is comparable with effect of atropine, but tsikloplegichesky and mydriatic action stronger and less long. The mydriasis develops in 5-10 minutes after instillation and reaches a maximum by 15-20 minute. Mydriasis remains within 1 hour (when using 0.5% of solution) and 2 hours (when using 1% of solution).
The maximum paralysis of accommodation after 2-fold instillations of 1% of solution on average arises in 25 minutes and remains within 30 minutes. Full stopping of paralysis of accommodation comes in 3 hours.

Indications
– when carrying out an oftalmoskopiya and determining a refraction
– before surgical (extraction of a cataract, retina and vitreous surgery) and laser operations (retina lazerkoagulyation)
– inflammatory diseases of eyes (as a part of complex therapy) and in the postoperative period for prevention of development of synechias.

The route of administration and doses
For definition of a refraction dig in 1-2 drops of 1% of solution 2 times with an interval of 5 minutes. For prolongation of effect one more burying can be added.
After burying it is recommended to press a plaintive tubule at an internal corner of an eye. It reduces system absorption of medicine and serves as prevention of development of adverse system reactions.
It is not necessary to touch with a pipette tip eyes, or any other surface to avoid pollution of contents of a bottle.
Use of 1% of Midriatsila solution is not recommended to children up to 6 years (only 0.5% solution).

Side effects
Local:
– accommodation disturbance
– decrease in visual acuity
– increase in intraocular tension
– development of a bad attack of closed-angle glaucoma
– allergic reactions
– photophobia
System:
At absorption of ingredients of drug in rare instances can be noted:
– concern, excitement, dryness in a mouth, a dysuria, a hyperthermia, a headache, tachycardia, arterial hypotension.

Contraindications
– glaucoma, especially closed-angle and mixed primary glaucoma
– hypersensitivity to drug components
– diseases of a cardiovascular system of heavy degree.

Medicinal interactions
due to the system effects of Midriatsil which are shown even at local use there can be strengthening of anticholinergic effects of other pharmaceutical means (for example, antihistamines, tricyclic and tetracyclic antidepressive means, procaineamide, quinidine, MAO inhibitors) possessing partial parasympatolytic action.
Tsikloplegichesky action of Midriatsil amplifies at its simultaneous use with simpatomimeticheskimy drugs, is weakened at use with parasimpatomimeticheskimy drugs.
Perhaps more significant increase in intraocular pressure at patients with a narrow corner of an anterior chamber at simultaneous use of Midriatsil and nitrates, nitrites, a haloperidol.

Midriatsil should appoint the special instructions Pregnancy and the period of a lactation pregnant women and the feeding women only if the expected therapeutic effect exceeds potential risk for a fruit.
Contact lenses
As Midriatsil contains chloride a benzalkoniya, it is necessary to delete soft (hydrophilic) lenses during burying. Lenses can be dressed not earlier than in 15 minutes after burying.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
After use of drug owing to change of accommodation and width of a pupil, decrease in visual acuity is possible therefore use of drug is not recommended to drivers of motor transport in evening and night time.
Use in pediatrics
is not recommended to Children up to 6 years Midriatsil’s use.

The overdose
At an excess dosage or poisoning with Midriatsil (in case of administration of drug inside), typical symptoms is dryness of skin and mucous membranes, tachycardia, expansion of pupils, excitement, spasms at high doses – a coma and paralysis of breath.
Treatment: at emergence of symptoms of overdose it is necessary to wash out a stomach and to accept activated carbon. In hard cases it is possible to enter intravenously 1-2mg physostigmine. Introduction of this means can be repeated with an hour interval. In spasms it is necessary to enter 10-20mg Diazepam intravenously. At manifestation of a hyperthermia it is necessary to take physical measures of cooling.

A form of release and packing
Eye drops of 1%, 15 ml in bottles from white opaque plastic with Drop-Tainer™ dropper doser. Each bottle together with the instruction for use is packed into a cardboard box.

To Store storage conditions in vertical position at a temperature from +80 to + 300C.
To store in the places inaccessible for children!

3 years
not to apply a period of storage after an expiration date.
A period of storage after the first opening – 1 month at a temperature of storage from +80 to + 300C.

Prescription status
According to the prescription

the Producer
of page and. Alkon-Kuvrer of N of century (s. a. Alcon-Couvreur n.v.)
B-2870 of Puurs, Belgium

Additional information