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Hydrocortisone-Akos 1% 10g ointment tube




The instruction
for medical use


the Trade name

the International unlicensed

name Hydrocortisone Dosage Form Ointment, 1%

of 100 g of ointment contains
active agent – Hydrocortisoni acetas of 1.0 g,
excipients: vaseline medical, lanolin, pental, stearic acid, methylparahydroxybenzoate, propilparagidroksibenzoat, water

the Ointment purified the Description white with a yellowish shade or light yellow color

Pharmacotherapeutic group
Glucocorticosteroids for topical treatment of diseases of skin. Glucocorticoids. Glucocorticosteroids slaboaktivny (group I). Hydrocortisone.
The ATX D07AA02 code

the Pharmacological

Pharmacokinetics Later properties of applique collects in epidermis (generally in a granular layer). It is metabolized directly in epidermis, and further in a liver. It is allocated with kidneys and intestines.
The pharmacodynamics
the Hydrocortisone is synthetic glucocorticosteroid drug for external use. Has anti-inflammatory, antiedematous, antipruritic effect. Slows down release of cytokines (interleukins and interferon) from lymphocytes and macrophages, release by eosinophils of mediators of inflammation oppresses, breaks metabolism of arachidonic acid and synthesis of prostaglandins. Stimulating glucosteroid receptors, induces formation of a lipokortin. Reduces inflammatory cellular infiltrates, reduces migration of leukocytes and lymphocytes, including lymphocytes to the area of inflammation. When assigning in the recommended doses does not cause system side effects.

– eczema
– allergic and contact dermatitis
– neurodermatitis
– psoriasis
– an erythrosis
– a prurigo
– stings of insects
– seborrhea

the Route of administration and doses
Outwardly. Ointment is applied a thin layer on affected areas of skin by 2-3 times a day. Duration of a course of treatment depends on the nature of a disease and efficiency of therapy, being, as a rule, 6-14 days, at the persistent course of the disease it can be prolonged up to 20 days. On the limited centers for strengthening of effect it is possible to use occlusive bandages. At use of ointment for children of 2 years is also more senior it is necessary to limit the general duration of treatment to term – no more than two weeks and to exclude the actions leading to steroid absorption strengthening (warming, fixing and occlusive bandages).

Side effects
– hyperaemia, puffiness and an itching in sites of application of ointment
It is very rare
– at prolonged use possibly development of secondary infectious damages of skin, atrophic changes in it, a hypertrichosis
– at prolonged use of ointment or use of an occlusive bandage, especially on big sites of defeat, development of symptoms of a hypercorticoidism (hyperglycemia, a glucosuria, reversible oppression of function of bark of adrenal glands, manifestation of a syndrome of Cushing) is possible as manifestation of resorptive action of a hydrocortisone

of the Contraindication
– hypersensitivity to a hydrocortisone or other components of drug
– wound, skin cankers
– bacterial, viral and fungus diseases of skin
– a tuberculosis cutis and syphilitic damages of skin
– a rozatse
– vulgar eels
– perioral dermatitis
– skin tumors
– children’s age (up to 2 years)
– pregnancy

Medicinal interactions
is not established.

Special instructions
With care: lactation period, diabetes, tuberculosis (systemic lesion).
In cases of use of drug for children, or under occlusive bandages duration of a course of treatment needs to be reduced by area of the person up to two weeks. At children’s age the suppression of function of bark of adrenal glands can quicker develop. Besides, decrease in secretion of growth hormone can be observed. At drug use it is necessary to watch the body weight, growth, concentration of cortisol of plasma for a long time. To children up to 12 years drug is appointed only under medical control.
It is necessary to avoid hit of ointment in eyes and mucous membranes.
If after 7 days of use there does not occur improvement or aggravation of symptoms is observed, use of drug it is necessary to stop and see a doctor. In case of resuming of symptoms in several days after drug withdrawal it is necessary to consult with the doctor.
At long-term treatment and/or drawing it is recommended to appoint a diet with restriction of sodium and the increased potassium content to big surfaces, to enter enough protein into an organism.
It is necessary to control arterial blood pressure, glucose content in blood, blood clotting, a diuresis, body weight of the patient, plasma cortisol level.
For prevention of infectious damages of skin drug is recommended to appoint in combination with antibacterial and antifungal agents.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
are not revealed.

The overdose
Acute overdose is improbable, however, at excessive or prolonged use of drug the chronic overdose which is followed by signs of a hypercorticoidism is possible: hyperglycemia, glucosuria, reversible oppression of function of bark of adrenal glands, manifestation of a syndrome of Cushing.
Treatment: the corresponding symptomatic treatment is shown. In case of chronic toxic action the gradual drug withdrawal is recommended.

A form of release and packing
On 10 g in tubas aluminum.
Each tuba together with the instruction for medical use in the state and Russian languages is placed in a pack from cardboard.

To Store storage conditions at a temperature from 8 °C to 15 °C.
To store out of children’s reach!

3 years
not to use a period of storage after an expiration date.

Prescription status
According to

ProizvoditelOAO’s prescription Synthesis. Russia, 640008, Kurgan, Konstitutsii Avenue, 7 Ph./fax (3522) 48-16-89E-mail: real@kurgansintez.ruinternet-website:
the Owner registration udostovereniyaoao Synthesis, the Russian Federation
the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality produktsiitoo STOFARM, 000100, Republic of Kazakhstan, Kostanay region, Kostanay, Uralskaya St., 14 ph. 714 228 01 79

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