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Galavit 100 mg 5’s powder for solution intramuscularly

$55.00

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Description

The instruction for medical use of Galavit Torgovoye medicine a name of Galavit® the International unlicensed name Is not present the Dosage form Powder for preparation of solution for intramuscular introduction 50 mg and 100 mg Structure One bottle contains active agent – Галавит® 50 mg or 100 mg the Description Crystal powder of color, white or white with a yellowish shade, Pharmacotherapeutic group Immunomodulators the ATX L03 Code the Pharmacological Pharmacokinetics of Galavit® properties are quickly soaked up, gets into bodies, fabrics and biological liquids. The maximum concentration in blood plasma at intramuscular introduction is reached in 18-21 min. Communication with proteins of plasma – 6%. The maximum concentration of drug is in kidneys, minimum in muscles and tissues of a brain. Absolute bioavailability of Galavita® at intramuscular introduction of 59%. Drug gets through a blood-brain and placental barrier. It is brought out of an organism, generally through kidneys. After an intramuscular injection the elimination half-life of drug makes 30-40 minutes. The pharmacodynamics of Galavit® is applied as immunomodulatory and anti-inflammatory drug in complex therapy of immunodeficiency. The mechanism of effect of drug is connected with its ability to influence functional and metabolic activity of phagocytal cells (monocytes/macrophages, neutrophils, natural killers). Besides, Galavit® normalizes antibodyformation, indirectly stimulates development of endogenous interferon (IFN-α, IFN-γ). In inflammatory diseases drug reversibly for 6-8 hours inhibits excess synthesis by hyper elicited macrophages of a factor of necrosis опухолей-α, interleukin-1, interleukin-6 and other pro-inflammatory cytokines, active forms of oxygen which level defines extent of inflammatory reactions, their recurrence and also severity of intoxication and level of an oxidatic stress. Normalization of a functional condition of macrophages leads to restoration of the antigen presenting and regulating function of macrophages, decrease in level of an autoaggression. Stimulates bactericidal activity of neutrocytes, strengthening phagocytosis and increasing nonspecific resistance of an organism to infectious diseases. The main pharmacological effects (immunomodulatory and anti-inflammatory) are observed within 72 hours. Indications At adults and children are more senior than 12 years as a part of complex therapy – a peptic ulcer of a stomach and a 12-perstny gut – a viral hepatitis And, In, With – the chronic recurrent diseases caused by a virus of herpes of the 1 and 2 type – the diseases caused by human papillomavirus – infectious and inflammatory urogenital diseases (an urethritis of a chlamydial and mecotic etiology, chlamydial prostatitis, an acute and chronic salpingo-oophoritis, an endometritis) – pyoinflammatory diseases of bodies of a small pelvis – postoperative rehabilitation of patients with a hysteromyoma – complications of the postoperative period at women of reproductive age, – postoperative is purulent – septic complications and their prevention (including, at oncological patients) – a chronic recurrent furunculosis, an ugly face – asthenic states, neurotic and somatoformny disorders, decrease in physical effeciency (including, at athletes), mental, behavioural and post-abstinent disorders in alcohol and drug addiction – inflammatory diseases of a mucous membrane of an oral cavity and throat, a parodont disease. Adults and children from 12 years in monotherapy have acute and chronic infectious and inflammatory diseases of digestive tract which are followed by intoxication and/or diarrhea – persistent urogenital infections, including when holding immunorehabilitation actions during the interrecurrent period for the purpose of maintenance of clinical remission. At children 6 years as a part of complex therapy – purulent surgical diseases (burn defeats, a recurrent furunculosis, chronic osteomyelitis, gangrenous appendicitis with an omentitis, peritonitis, purulent pleurisy), – frequent recurrent respiratory diseases and ENT organs of a bacterial and virus etiology (frequent SARS, bronchitis, pneumonia, an adenoid disease, chronic otitis, a chronic adenoiditis) are more senior. The route of administration and doses At adults and children are more senior than 12 years as a part of complex therapy Intramusculary. Before introduction drug is dissolved in 2 ml of water for injections or 0.9% chloride sodium solution. Doses, frequency rate of introduction and duration of use are selected the doctor depending on the diagnosis, disease severity, age of the patient. – In a peptic ulcer of a stomach and a 12-perstny gut in an acute period: 2 days on 200 mg once a day, then on 100 mg with an interval of 72 hours. Course of 15-25 injections. In the chronic period: 5 days on 100 mg once a day, then on 100 mg in 72 hours. Course of 20 injections. – In a viral hepatitis And, In, With an initial dose makes 200 mg once, then on 100 mg 2 times a day before stopping of symptoms of intoxication and inflammation. The subsequent continuation of a course on 100 mg with an interval of 72 hours. Course 20 – 25 injections. – In the chronic recurrent diseases caused by a herpes virus 1 and 2 types: on 100 mg daily 5 injections, then on 100 mg every other day 15 injections. A course – 20 injections. – In the diseases caused by a virus of papilloma of 5 days on 100 mg once a day then on 100 mg every other day 15 injections. A course – 20 injections. – In urogenital diseases – an urethritis of a chlamydial and mecotic etiology, chlamydial prostatitis 1 day on 100 mg twice, then on 100 mg every other day. A course of 10-15 injections (depending on weight of pathological process). – In a salpingo-oophoritis, an endometritis during an acute period 2 days on 200 mg once a day, then on 100 mg with an interval of 72 hours, duration of use depends on disease severity. In total on a course of 20 injections. In the chronic period – 5 days on 100 mg once a day, then on 100 mg every 72 hour. Course of 20 injections. – In acute and chronic purulent diseases of bodies of a small pelvis: in an acute period – 1 day of 200 mg once, 3 days on 100 mg daily, then on 100 mg every other day 5 injections. Course of 9 injections. In the chronic period – 5 days on 100 mg once a day, then 100 mg every 72 hour. A course – 20 injections. – For postoperative rehabilitation of patients with a hysteromyoma and at complications of the postoperative period at women of reproductive age: 5 days on 100 mg once a day, then on 100 mg every other day. A course – 15 injections. – For prevention and treatment of postoperative infectious complications in to – and the postoperative period (including, at oncological patients) appoint on 100 mg 5 injections before operation, 5 after operation on 100 mg every other day and 5 injections on 100 mg of c an interval of 72 hours once a day. A course – 15 injections. At a severe disease an initial dose of 200 mg once or 2 times a day on 100 mg. – In a chronic recurrent furunculosis, an ugly face – 5 days on 100 mg once a day, then on 100 mg every other day. Course of 20 injections. – At asthenic states, neurotic and somatoformny disorders, in mental, behavioural and post-abstinent disorders, at patients with alcohol and drug addiction: 5 days on 100 mg daily, then on 100 mg in 72 hours. Course of 15-20 injections. For increase in physical effeciency: on 100 mg every other day – 5 injections, then on 100 mg in 72 hours, a course up to 20 injections. – In inflammatory diseases of a mucous membrane of an oral cavity and throat, parodont diseases: an initial dose of 100 mg daily 5 injections, then on 100 mg with an interval of 72 hours. Course of 15 injections. At adults and children 12 years in monotherapy – the Acute and chronic infectious and inflammatory diseases of digestive tract which are followed by intoxication and/or diarrhea are more senior: 200 mg once, then on 100 mg 2 times a day before stopping of symptoms of intoxication. The subsequent continuation of a course on 100 mg with an interval of 72 hours is possible. Course of 20-25 injections. – Persistent urogenital infections, including, when holding immunorehabilitation actions during the interrecurrent period for the purpose of maintenance of clinical remission: on 100 mg every other day a course in 10 injections. At children 6 years as a part of complex therapy are more senior – In purulent surgical diseases (burn defeats, a recurrent furunculosis, chronic osteomyelitis, gangrenous appendicitis with an omentitis, peritonitis, purulent pleurisy): children are from 6 to 12 years old on one injection 50 mg daily – 5 days, then on one injection of 50 mg every other day within 10 – 15 days. The course of 10-13 injections, to children is aged more senior 12 up to 18 years – treatment is carried out according to the same scheme in the form of intramuscular injections on 100 mg. When bandagings the external use of Galavita® in the form of bandages with the sterile napkins moistened with 1% – m Galavita® solution in water for injections is desirable (in bandages with the talker or water-soluble salve dressings). – In frequent recurrent respiratory diseases and ENT organs of a bacterial and virus etiology (frequent SARS, bronchitis, pneumonia, an adenoid disease, chronic otitis, a chronic adenoiditis): children are from 6 to 12 years old on one injection 50 mg daily within 5 days, then on 50 mg once a day every other day within 10 – 15 days. Course of 10-13 injections. To children is aged more senior 12 up to 18 years – treatment according to the same scheme in the form of intramuscular injections on 100 mg. For patients of advanced age of a dose are not adjusted. Side effects Seldom (from 0.01% to 0.1%) – allergic reactions from skin and hypodermic fabrics: skin rash, an itching, a small tortoiseshell of the Contraindication – individual intolerance of drug – pregnancy – the lactation period – children’s age up to 6 years (there is no clinical experience of use). Medicinal interactions At simultaneous use the decrease in course doses of antibiotics is possible. Cases of incompatibility with other medicines are noted. The special instructions Use in pediatrics do not appoint Drug to children up to 6 years. Pregnancy and the period of a lactation do not appoint Drug to pregnant women, women during breastfeeding of Feature of influence of medicine on ability to run the vehicle and potentially dangerous mechanisms does not influence. Overdose of Data on cases of overdose there is no drug Galavit®. The form of release and packing On 0:05 g and 0.1 g of drug place in the bottles for injections with a capacity of 5 ml or 10 ml corked by rubber bungs and rolled by aluminum caps. On 3 or 5 bottles together with the instruction for medical use in the state and Russian languages place in a pack from cardboard. To Store storage conditions at a temperature from 15ºС to 25ºС in the place protected from light. To store out of children’s reach! 4 years not to apply a period of storage after an expiration date. Prescription status According to the prescription LLC Selvim Producer, Russian Federation, 308013, Belgorod, Rabochaya St., 14. Owner of the registration certificate of LLC Selvim, Russian Federation, 123290, Moscow, Magistralny Deadlock of the 1st, 5A, lump. 91. Ph. / fax (495) 269-03-43, 269-03-44. The address of the organization accepting claims on quality of products from consumers in the territory of RK ALDIMED LLP, 050051, Republic of Kazakhstan, Almaty, mdt. Samal-1, house 1. Ph. / fax (727) 263-27-34.
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