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Foul Ferlatum 10s 15 ml oral solution

$30.10

32b861696a41

Description

Trade name

Ferlatum Fol

the International unlicensed name

Is not present

the Dosage form

Solution for intake

Structure

One bottle contains

active agent – iron a protein suktsinilat 800 mg

(it is equivalent gland (III) 40 mg),

excipients: sorbitol, propylene glycol, sodium methylparahydroxybenzoate, sodium propilparagidroksibenzoat, fragrance cherry, sodium saccharin, water purified.

The cap doser contains

active agent of calcium of the folinat of pentahydrate of 0.235 mg (0.200 mg of calcium of the folinat and 0.185 mg of folinovy acid are equivalent),

excipient Mannitolum.

The description

In a bottle transparent brown solution with a pleasant characteristic smell.

Cap doser contents – a white homogenous powdery mixture, flavourless.

Pharmacotherapeutic group

Iron preparations (trivalent) for intake in a combination with folic acid. The code of automatic telephone exchange B03AD01 the Pharmacological

Pharmacokinetics Carrying Out properties of traditional pharmacokinetic researches for the iron containing additional elements in structure is not possible as proteinsuktsinilat it is split by gastric juice, and iron is soaked up in the form of ions, in quantity, depending on requirements of an organism. In normal conditions of loss of iron by the person are very insignificant. The most part of iron is lost in menstrual bleeding, in very insignificant quantity is lost with bile, with then and when peeling integuments.

A pharmacodynamics

Ferlatum Fol original antianemic drug which represents the iron-protein complex received by a suktsinilirovaniye of milk protein of casein in association with folinovy acid. Thanks to the profile the protein suktsinilat pretsipitirut solubilities of iron in acidic environment of a stomach, holding iron in the connected state. On alkaline Wednesday of a 12-perstny gut the complex becomes soluble again, at the same time the protein fraction is split thanks to influence of pancreatic proteases, and iron is released and soaked up by a mucous membrane of a gut. Folinovy acid is biologically active form of folic acid which is true active vitamin ingredient. Use of folate in the form of folinovy acid allows to bypass some metabolic stages and to fill up reserves of vitamins, even in the absence of liver and medullary enzymes which transform folic acid to its biologically active form. Folinovy acid plays an important role in synthesis of purines and pyrimidines that is necessary for DNA synthesis, especially in the course of a hematopoiesis. Folinovy acid is effective in anemia owing to deficiency of folate.

Indications

– therapy of the hidden and demonstrated forms of deficiency of iron (iron deficiency anemias) and folates, owing to insufficient consumption with food or insufficient absorbability of iron, against the background of sharp or chronic blood loss or infectious process at patients of any age (children and adults)

– prevention of deficiency of iron and folates during pregnancy and feeding by a breast and active growth

the Route of administration and doses

Before use need to be removed from a cover a protective strip in the direction of an arrow. Then to press with a force the red kolpachokdozator which is in a cover, having shipped it in a bottle against the stop. At the same time powder from a cap doser pours out in a bottle. It is vigorous to shake up contents of a bottle. To remove a cap doser and to drink solution.

Ferlatum Fol accept inside, to or after a meal.

Adults: on 15 ml 1 or 2 times a day (in the quantity equivalent to 40-80 mg of Fe3 + and 0.235-0.470 mg of calcium of the folinat of pentahydrate).

Children since the neonatality period: 1.5 ml/kg/days (in the quantity equivalent to 4 mg/kg/days of Fe3 + and 0.0235 ml/kg/days of calcium of the folinat of pentahydrate), in two steps.

Pregnant women:

For prevention of an iron deficiency anemia on 1 bottle a day.

For treatment of latent or clinically apparent deficiency of iron on 1-2 bottles a day in two steps.

After achievement of normal indicators of serumal iron and hemoglobin the treatment is continued within not less than 8-12 weeks, appointing a maintenance dose.

Side effects

– gastrointestinal disorders (diarrhea, a constipation, nausea, pain in epigastriums) which disappear at decrease in a dosage or drug withdrawal

of the Contraindication

– hypersensitivity to active and auxiliary components of drug

– a hemosiderosis, hemochromatosis

– iron utilization disturbance (lead anemia, sideroakhrestichesky anemia)

– not iron deficiency anemias (hemolytic anemia, the megaloblastny anemia caused by a lack of B12 vitamin)

– chronic pancreatitis, cirrhosis

Medicinal interactions

Iron preparations break processes of absorption of tetracyclines, bisfosfonat, antibacterial drugs of derivatives of a hinolon, Penicillaminum, thyroxine, a levodopa, karbodopa, alpha Methyldopums in digestive tract. An interval between reception Ferlatum Fol and the listed drugs has to make not less than 2 hours.

The absorbability of iron can be increased at co-administration more than 200 mg of ascorbic acid and is reduced at use of antacids. Chloramphenicol causes the delayed response to therapy by iron.

At simultaneous use Ferlatum Fol with blockers of H2-histamine receptors the pharmacological interaction is absent. Some antineoplastic and antileukemic preparataa (aminotreptin, a methotrexate and other pterinovy derivatives) behave as antagonists of folates.

The Continuous period of use Ferlatum Fol should not exceed special instructions 6 months, except for cases of chronic blood losses (menorrhagias, hemorrhoids, etc.) and pregnancies.

In the presence the patient has anemias, before a therapy course, it is recommended to establish its reason. Owing to existence in composition of drug of Ferlatum Fol milk protein it has to be applied with care at the patients who are suffering from intolerance of milk and having allergic reactions to milk protein. Drug contains sorbitol therefore it should not be appointed to patients with rare hereditary hereditary intolerance of fructose. Ferlatum Fol contains parabens (sodium methylparahydroxybenzoate, sodium propilparagidroksibenzoat) that can cause the delayed allergic reaction.

Pregnancy and the period of a lactation

Use of drug during pregnancy and feeding by a breast does not demand special precautionary measures.

Features of influence on ability to run the vehicle or potentially dangerous mechanisms

the Overdose

Symptoms does not influence: the first 6-8 hours after reception of overdoses of drug are celebrated epigastric pains, nausea, vomiting (sometimes with blood), diarrhea, drowsiness, pallor of integuments, development of a coma is possible.

Treatment: immediate prescribing of emetic drugs, if necessary gastric lavage and symptomatic treatment. Also if necessary the iron-chelating agent Deferoxaminum can be applied.

A form of release and packing

On 15 ml of drug in the colourless opaque polyethylene bottles corked by the pulling polymeric covers with a strip for opening with the doser sealed in a cover by a cap.

10 bottles together with the instruction for use in the state and Russian languages place in a cardboard box.

To Store storage conditions at

a temperature not higher than 25 Store OS out of children’s reach!

A period of storage

2 years

not to use drug after an expiration date.

Prescription status

According to the prescription

The producer Italpharmako S.A., Madrid, Spain

San Rafael3, 28108 Alkobendas, Madrid

the Owner of the registration certificate

S. Italpharmako of the item. And.,

Milan, Italiya Viale Fulvio Testi, 330, Milan

Additional information

Ingredient

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