Antifungal agents / Dermatology / External Use / Fungus of the skin, nails

Candid B 1g of 15% cream in the tube

Brands: Glenmark (India)

$19.30

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Candid B 1g of 15% cream in the tube quantity

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Sku:

8887e86685a5

Brands:: Glenmark (India)

Description

The instruction for use
of medicine for
Candide’s experts – B

the Trade name
of Candide – B

the International unlicensed name
Is not present

the Dosage form
Cream of 15 g

Structure
100 g of cream contain
active agents:
Clotrimazolum of 1000 mkg
beclomethasone of 25 mkg,
excipients: white vaseline jelly, liquid paraffin, tsetomoakrogol wax, benzyl alcohol, methylparaben, propylparaben, bottled hydroxytoluene, propylene glycol, monosubstituted sodium phosphate, anhydrous phosphate sodium, purified water.

The description Cream of white color of uniform consistence

Pharmacotherapeutic group
Other antifungal drugs for topical administration. The combined drugs.
The code of automatic telephone exchange D01AE20

the Pharmacological

Pharmacokinetics At properties topical administration Clotrimazolum is badly soaked up from the surface of skin (collects in a corneal layer of epidermis).
Beclomethasone possesses system absorption at prolonged use of cream. Its active metabolite of beclomethasone Dipropionas is quickly soaked up, time of achievement of the maximum concentration in blood plasma (Tmax) is 3 hours. Communication with proteins of blood plasma rather high – 87%. Beclomethasone Dipropionas has high plasma clearance. Elimination half-life of 0.5 h.
Receipt in a blood stream and system manifestations depend on a total dose of ointment and extent of hydration of skin.

Candide’s pharmacodynamics of B — the combined antifungal drug for external use with an anti-inflammatory component. Pharmacological effect of drug is caused by the properties of Clotrimazolum and beclomethasone of Dipropionas which are its part. Clotrimazolum — the antifungal broad-spectrum agent relating to group of derivatives of an imidazole. Dermatophytes, barmy mushrooms (sorts Candida, Torulopsis glabarata, Rhodotorula), mold mushrooms and also activators multi-colored are sensitive to Clotrimazolum depriving also of an erythrasma. Besides, Clotrimazolum is effective concerning gram-positive (staphylococcus, streptococci) and gram-negative bacteria (Bacteroides, Gardnerella vaginalis) and also in relation to Trichomonas vaginalis, Malassezia furfur, Corinebacterium minussimum. The effect of Clotrimazolum is connected with ability to break synthesis of ergosterol which is a part of a cellular membrane of mushrooms. As a result of it the structure and properties of membranes change, killing is observed. Beclomethasone Dipropionas — the synthetic glucocorticosteroid — renders anti-inflammatory, antiallergic, anti-exudative and antipruritic action. The mechanism of action of system use of glucocorticosteroids consists in oppression of all phases of inflammation: contacting specific steroid receptors, they get into a kernel of a cell and connect to DNA, stimulate formation of information RNA, as a result of broadcast of RNA on ribosomes various regulatory proteins are synthesized — the most important of them metokortin inhibits enzyme A2 phospholipase and by that synthesis of prostaglandins and leukotrienes playing a key role in development of inflammation at all allergodermatoza
Indications
Fungal infections of skin, especially oppresses if they are followed
by acute eczematic manifestations:
– dermatomycoses of various parts of a body
– an epidermophitia of feet
– the dermatosis complicated by consecutive infection.

A route of administration and doses
to Wash out and dry an affected area. Then to put Candide to B cream. On hairy parts of the body before putting cream it is necessary to move apart hair for achievement of direct contact with an affected area. Drug is used 2–3 times a day.After disappearance of symptoms of eczema it is recommended to pass to treatment with Candide’s cream before total disappearance of primary fungal
infection. Duration of treatment of a dermatosis usually is 3–4 weeks, an erythrasma and a chromophytosis — about 3 weeks.

Side effects
of Candide of B cream is usually well transferred.
Seldom -erubescence, burning sensation and prickings in the site of application of drug
Very seldom
– a skin atrophy, hypopigmentation, acneform rash, a contact dermatosis. At emergence of irritation, drug needs to be cancelled.
At prolonged use are possible – an Icenco-Cushing syndrome
– increase in arterial blood pressure
– a hyperglycemia
– osteoporosis
– exacerbation of a peptic ulcer of a stomach and 12 items to., ulcerations of a digestive tract
– headaches, dizziness
– a cataract, glaucoma
– a growth inhibition at children and teenagers
– a lymphopenia, an eosinophilia
– a Quincke’s disease.

Contraindications
– a tuberculosis cutis
– chicken pox
– a herpes simplex
– measles
– syphilitic skin rashes
– hypersensitivity to drug components
– pregnancy and a lactation
– children’s age up to 2 years.

Medicinal interactions
Are not present data on interaction of drug with other medicines.

The special
instructions Drug it is intended for use only in dermatological practice. At use of cream, system side reactions are excluded if only drug is not applied on open wounds or with occlusive dressings.

To apply use in pediatrics With care at children from 2 to 16 years in view of a possibility of the increased penetration through skin and development of toxic system reaction. Use of a hermetic bandage for children up to 5 years is not recommended. Use of cream in children’s practice has to be carried out strictly under observation of the doctor.
Influence on ability to driving of motor transport and to control of mechanisms Does not influence
Overdose
the Acute overdose at local drawing Candide of B is improbable
and cannot pose a threat for life.

A form of release and packing
In tubas aluminum on 15 g, in a pack a cardboard 1 tuba with
the instruction for use

Storage conditions
In the dry, protected from light place at a temperature below 25º C.
Short-term temperature drop to 40º C is allowed.

To store out of children’s reach!

A period of storage
3 years
not to use after an expiration date

Prescription status
According to the prescription

Glenmark Pharmasyyutikalz Ltd Producer, B/2, Mahalaxmi Chambers, 22
Bhulabhai Desai Road, Mumbai 400,026, India.

Additional information