The instruction for use of medicine for experts
the Trade name
Mezhdunarodnoye the unlicensed name
of Hyoscine butylbromide
the Dosage form
Suppositories rectal 10 mg
1 suppository contains
active agent – hyoscine – N – of butylbromide, 10 mg
excipients: the distilled water, solid W 45 fat.
White or colors of ivory, smooth, oblong suppositories with a wax smell.
Semi-synthetic alkaloids of a belladonna, quarternary ammonium connections.
The code of automatic telephone exchange A03BB01
Has spasmolytic effect on smooth muscles of internals (gastrointestinal, bilious and urinogenital paths), reduces secretion of digestive glands. Being quarternary ammonium derivatives, hyoscine – N – butylbromide does not get through a blood-brain barrier therefore anticholinergic influence on the central nervous system (CNS) is absent.
– spastic conditions of a gastrointestinal, bilious and urinogenital path (renal colic, bilious colic, intestinal colic, cholecystitis, a pylorospasm)
– spastic dyskinesia of biliary tract and a gall bladder
– a peptic ulcer of a stomach and duodenum in an aggravation phase (as a part of complex therapy)
The route of administration and doses
Adults and children are more senior than 6 years: rektalno on 1 – 2 suppository 3 times a day.
Suppositories should be taken from a cover and to enter into a rectum the pointed end forward.
– dryness in a mouth, dryness of integuments
– accommodation paresis
– is possible an ischuria which is usually not expressed and is allowed independently
– to hypersensitivity reaction with skin manifestations
– emergence of the complicated breath
of the Contraindication
– hypersensitivity to hyoscine – N – to butylbromide or any other component of drug
– closed-angle glaucoma
– a myasthenia
– children up to 6 years
It is necessary to appoint with care drug in the following clinical situations: suspicion on intestinal impassability (including a pyloric stenosis), obstruction of urinary tract (including prostate adenoma), tendency to tachyarrhythmias (including a ciliary tachyarrhythmia).
Pregnancy and a lactation
It is necessary to appoint with care drug during pregnancy, especially in the first trimester. In need of use of drug it is necessary to estimate potential advantage of therapy for mother and possible risk for a fruit.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms.
It is necessary to be careful at the driving of the car and occupations with other potentially dangerous types of activity demanding increase in attention and speed of psychomotor reactions.
So far cases of overdose of BUSKOPANOM are not described therefore the following symptoms can be connected with its pharmacological effect.
Symptoms: possible development of anticholinergic symptoms – an ischuria, dryness in a mouth, erubescence, tachycardia, oppression of motility of digestive tract and also passing disorders of vision.
Treatment: symptoms of overdose of BUSKOPANA are stopped by cholinomimetics. To patients with glaucoma locally appoint pilocarpine in the form of eye drops. If necessary cholinomimetics enter systemically, for example, neostigmin 0.5-2.5 mg intramusculary or intravenously. Cardiovascular complications treat according to usual therapeutic rules. In paralysis of respiratory muscles the intubation, artificial ventilation of the lungs is shown. In case of an ischuria catheterize a bladder. Maintenance therapy is carried out.
A form of release and packing
Suppositories rectal on 10 mg.
In packing of 10 suppositories. IInstruktsiya on use is placed in a cardboard pack.
In the dry place at a temperature are not higher +25ºС.
To store out of children’s reach!
Not to use an expiration date of 5 years after expiry date.
of Proiswoditel Boehringer Ingelcheim International GmbH, Germany,
it is made by Institut de Angueli of S.R. L., Italy